This study aims to compare the water quality of Ghorveh plain (one of the main centers of potato production) and Marivan plain (one of the main centers of tobacco production) in the east and west of Kurdistan province, respectively. Total anions, total cations, chlorine, sulfate, bicarbonate, potassium, calcium, magnesium, sodium ions and sodium absorption ratio, alkalinity, total hardness, total dissolved solids and electrical conductivity data of groundwater in both plains were compared in between 1998 to 2016 by drawing water quality diagrams, calculation of indices, determination of different ionic ratios and groundwater quality mapping using GIS. To illustrate the distribution of data, chi-square test at 95% confidence and to compare the variables, independent t-test at the confidence level of 99% were used. The results showed that in both Ghorveh and Marivan plains, the order of concentrations of cations (from high to low) was calcium, magnesium, sodium and potassium, and the order of anions concentrations (from high to low) was bicarbonate, sulfate and chlorine. Based on the results, there is not any significant difference between the mean values of bicarbonate, potassium, calcium, alkalinity, total hardness and CO2 saturation index in groundwater of Marivan and Qorveh plains. The mean values of other studied variables, ion ratios and indices were significantly different at the 99% confidence level.