The issue of religious endowment and donation in Islamic societies, especially in Islamic Republic of Iran, has of vital importance. Although there are a lot of endowed estate in Iran, exploitation of this potentials are not progressive. The aim of this research, in regard to existing special consideration, is defining strategic policy for Iran Endowment & Reclamation Association to properly manage investment portfolio in realms of civil, agriculture, ranching, and mining by means of GE matrix and introduce the priorities. To reach this goal, after identifying the main potential fields in mentioned realms, the alternatives in each realm were introduced. Then, by means of some criteria for analyzing attractiveness of realms and fields and moreover some other criteria for analyzing strength of association for having activity in those realms and fields, realms and fields with higher priority were identified and introduced. The sample of the research, containing 17 people, was chosen from related experts. Survey has been the methodology of the research and the questionnaire has been used to collect data. Finally realms of civic and mining have been assessed as attractive realms and for activity in the 31 fields, strategic recommendations were proposed.