Purpose: This study aimed to compare the effectiveness of acceptance and commitment group therapy and cognitive-behavior group therapy on the body image dissatisfaction and interpersonal sensitivity in women with the body image dissatisfaction. Method: The research was experimental including a pretest-posttest design with two experimental groups and one control group along with the three-month follow-up. The statistical population consisted of females aged from 23 to 38 years with the body image dissatisfaction who had referred to the health centers of Tehran municipal during 2016-2017. The study sample was chosen through cluster sampling method. Four health homes were randomly selected from five zones of Tehran municipality. In this way, 453 people from the total of 20 health houses formed the sample size, which according to the cutting scores in the questionnaires, entry and exit criteria, 45 women were selected and randomly replaced in three groups. The research tools were Interpersonal Sensitivity Subscale Scale (SCL-90R) and others (Dragotis et al1984), multidimensional self-body questionnaire (Cash, 1997). The experimental groups consisted of 12 sessions, 90 minutes (weekly one session) under cognitive-behavioral group therapy and group therapy based on acceptance and commitment. Findings: The results of the mixed variance and Bonferroni analysis showed a significant increase in the body image satisfaction. While both therapies were effective on the body image satisfaction at the same level, a significant decrease of interpersonal sensitivity took place in the cognitive-behavior group therapy in the pretest, however, the result did not maintain in the follow-up.