Introduction: Dental caries are recognized as one of the most common chronic diseases and one of the most common childhood diseases, especially among populations with unfavorable social, economic and cultural conditions. The aim of this study was to determine the relationship between oral and dental health (CPQ) quality of life with PUFA (Pulpal involvement, ulceration, fistula and abscess) in children aged 8-10 years in Kermanshah in 2018 year. Materials and Methods: In this analytical cross-sectional study, 559 students from 1, 2, 3 educational districts in Kermanshah city in 2012 were selected by multistage sampling. Data were gathered through a demographic information form, a CPQ questionnaire, and a clinical examination. Data were analyzed using SPSS software version 25 and descriptive statistics (mean, standard deviation, frequency and percent), Pearson correlation, independent t-test and one-way ANOVA. Results: There was a direct and significant correlation between CP Q and PUFA and dmft index (P <0. 05). There was a direct and significant correlation between PUFA and dmft (P <0. 05). No significant relationship was found between PUFA and DMFT(P >0. 05). There was a significant difference between the average CPQ in terms of sex. The quality of life associated with oral health was higher in male students. Conclusion: The correlation between the quality of life of children and the level of dmft and PUFA showed that the higher CPQ score, and oral health problems, such as pain, eating and talking, increase the levels of dmft and PUFA.