The effects of different irrigation levels and plant densities on vegetative growth and seed yield of three soybean cultivars [Glycine max (L.) Merr.] were studied during 2000-2001. The experimental design used was split-factorial in a randomized complete block design (RCBD) with three replications on the Research Farm of Agriculture College at Shahid Bahonar University of Kerman. Irrigation levels (I1, I 2, I 3 and I4) were considered as the main plot and plant densities (D1, D2, D3 and D4) and soybean cultivars (V1, V2 and V3) as the subplots. The following plant characteristics were studied; plant height, number of nodes per main stem, internodes length in the main stem, leaf area index at flowering stage, plant dry weight, main root length, number of seeds per plant, seed yield per plant and harvest index. Results of this study showed that the highest and lowest rate of seed yield were obtained by irrigation treatments at I2 and I4, respectively (irrigation after 60 and 100 mm. evaporation from Class A pan). The highest rate of seed yield per plant was obtained from 30 plants per m2(D1) in Williams cultivar (V2) and the lowest from 60 plants per m2 (D4) in Hill cultivar (V3). Maximum and minimum plant height, number of nodes in the main stem, internodes length and leaf area index were obtained at I1 (irrigation after 40mm evaporation from Class A pan) and 14, respectively. Increasing the plant per unit area increased plant height, internodes length and leaf area index, but decreased the number of nodes in the main stem, plant dry weight and root length. Harvest index (HI) was highest at I2 level of irrigation, 40 plants per m2 ( D2 ) plant density and Hobbit ( V1 ) cultivar (I2D2V1 treatment), while it was lowest at I4 level of irrigation, D4 plant density and V3 cultivar (I4D4V3 treatment). Number of seed per plant was highly correlated with seed yield per plant, whereas root length was poorly correlated with grain yield per plant.