Background: The aim of this study was to compare symptoms of mental disorders of high-risk events drivers in the general population of Tehran.Materials and Methods: The study population consisted of drivers who had committed a violation. The method of causal-comparative was applied for a number of 400 male violating drivers and 398 ordinary citizens of Tehran using the MCMI-III questionnaire. Data were analyzed using the software SPSS 19.Results: The results showed that there were significant differences between the two groups in the scales of depression (3.12-T), histrionic personality disorder (11.9-T), antisocial personality disorder (43.96-T), negativistic personality disorder (13.58-T), anxiety disorder (13.58-T), manic disorders (4.88-T), drugs (13.58-T) and alcohol (10.92-T) of which high-risk events drivers demonstrated more symptoms. However, in other scales including schizoid, avoidant, dependent, narcissistic, borderline, other-abuse, obsessive, selfdestructive, schizotypal, and paranoid personality disorders, and somatoform, dysthymia, post-traumatic stress, thinking, major depression, and delusional disorders, there was no significant difference between the two groups.Conclusion: The findings suggest that during the preliminary examinations for drivers to prevent and reduce accidents by high-risk drivers comprehensive mental health screening procedures be performed.