Introduction: self-medication is a socioeconomic health problem in different communities. In this regard, there is a need for special attention to self-medication in parents especially those taking care of children. Therefore, the present research aimed to investigate the prevalence of self-medication in the parents of 1-8 year old children reffered to Shahid Mohammadi hospital in Bandar Abbas. Methods: The present descriptive-analytical study was conducted on 200 parents of 1-8 year old children reffered to Shahid Mohammadi hospital in Bandar Abbas. Participants were selected using simple randomized sampling method. Data collection tool was a researcher-made questionnaire that its validity and reliability were measured. Data were analyzed by SPSS software using descriptive and inferential statistics. Results: The results showed that 64% of parents had committed self-medication to their child. The most important causes of self-medication were easy drug supply from pharmacies with no prescription (71. 5%), availability of medications at home or by relatives(65. 5%), and previous experience of the disease (5305%). The most prevalent drugs taken were cold pills (99. 5%), sedatives (97. 5%), and antibiotics (52. 5%). Statistically significant correlations were found between the prevalence of selfmedication and Parents’ education (p-value<0. 001), insurance type (p-value=0. 013), and the number of children (pvalue< 0. 001). Conclusion: Since in the present research a high percentage of parents had tried self-medications for their children, it is essential to conduct educational programes to teach them the logical consumption of drugs and make them aware of the adverse effects of drugs.