Introduction: Student years at university are an important transitional period in which students undergo a lot of academic, occupational and living pressures. In this regard, the existence of suicidal ideation, also known as suicidal thoughts, among students has a wide range of negative psychosocial effects. The purpose of this study was to determinate the relationship between sense of coherence and cognitive emotion regulation with suicidal ideation in students.Materials and Methods: In this descriptive and correlational study, among all undergraduate and postgraduate students of the University of Mohaghegh Ardabili in 2017, 367 students were selected by a cluster sampling method. The suicidal revised questionnaires (SBQ-R), a short form of Antonovsky Integrity sense questionnaire and a short form of the Gravinsky Craig and Spinach on Critical Settlement Questionnaire were used for data collection. The research data were analyzed using descriptive statistics including frequency, mean and standard deviation and multiple linear regression in simultaneously method at a significant level of p<0.041.Results: The results showed that while a negative significant relationship between sense of coherence (r=-0.25) and cognitive emotion regulation (r=-0.32) with suicidal thoughts (p<0.011) was observed, correlation between suicidal ideation and cognitive-emotional confusion (r=0.27) was significantly positive. Also, the sense of coherence and cognitive adjustment of compatible and incompatible excitement predict about 23% of changes in suicidal ideation.Conclusion: Based on these results, the sense of coherence and cognitive adjustment of compatible and incompatible excitement can be related to the suicidal thoughts of students; therefore, it could be recommended that therapists and counselors especially who working at university counseling centers to take into account these considerations to reduce the rate of students' suicidal thoughts.