Purpose: The use of different models of training, especially combined training exercises are common among the elderly. The effect of combined training exercises on hormones and growth factors levels have been little studied in aging. The purpose of this study was to investigate the effect of 8 weeks concurrent training on growth hormone, IGF-1 serum concentration and GH/IGF-1 ratio in elderly women.Methods: In this quasi-experimental study with pre test and post test design, twenty-one healthy elderly women (55-70 years) were randomly placed into two groups, concurrent training (n=12) and control (n=9) groups. Training program was done eight weeks, 3 times per week. In order to compare data within and between groups, dependent t-test and independent t-test was used respectively.Results: The data showed GH, IGF-1 and GH/IGF-1 ratio were not significantly changed (P³0.05) following combined training. Also, a significant decrease observed in body mass (P=0.005), BMI (P=0.005) and body fat percentage (P=0.001) following 8 weeks combined training (P£0.05). VO2max increase significantly (P=0.024) Conclusion: In this study, 8 weeks of combined training led to non-significant increase in GH/IGF-1. Maybe, this training in long-term leads to changes in GH and IGF-1. Therefore, Due to improvements in body composition and aerobic power, maybe performing the long-term training program have a beneficial effect on the performance of the cardiovascular system and can be prevented from developing atherosclerosis.