Journal of Research in Urology
Year:2018 | Volume:2 | Issue:2 |Papers Count:5

Background and aim: The distinction between benign and malignant prostate lesions is one of the important issues in pathology. Misdiagnosis in these cases can lead to unnecessary treatments. The purpose of this study was to evaluate the diagnostic value of P504S sputum penetration in diagnosis of prostate cancer. Material and Methods: In this experimental study, 33 benign samples and 33 prostate malignant samples from needle biopsy were selected by available sampling method and the immunohistochemical marker P504S was determined. Following the pathology diagnostic method as a standard, the immunohistochemical marker P504S of benign cases was compared to malignant ones (P<0. 05). Results: Comparing the results of two methods of P504S staining and pathologic methods showed that there is a significant relationship between these two methods in the diagnosis of prostate malignancies. (P=0. 0001). Also, considering the pathologic diagnosis as the standard Gold method for diagnosis of prostate malignancies, all four sensitivity, specificity, positive predictive value and negative predictive value for P504S staining method in diagnosis of prostate malignancies was 97%. Conclusion: The findings of this study showed that this coloration has high sensitivity, specificity and high predictive value in evaluating the value of diagnosis of P504S staining method in diagnosis of prostate cancer. Therefore it can be used with high confidence in the differentiation of benign prostatic malignant lesions in diagnostic laboratories.

Background and aim: Despite surgical procedures for the treatment of urinary incontinence (SUI) in surgery, sling laparoscopy is known as a high-performance gold standard method. For the first time, in the present study, the efficacy of conventional laparoscopy was compared to Laparoscopy with Assistive Finger in women with SUI. Materials and Methods: Twenty-four patients with SUI between 2008-2010, who did not respond to routine drugs and cystocele repair were selected for standard laparoscopy. 18 patients with homogeneous age and gender where placed in the assistive finger technique group. In 1 year, two groups were followed up for improvement of symptoms, relapse, leakage rate and overall satisfaction of patients. Results: In the undergoing conventional sling laparoscopy group of treated patients (21 patients), 6 patients experienced relapse of disease symptoms. 3 patients, although the symptoms were partially removed, still had the leakage problem. Two patients, despite conducting cystoscopic controlling, nylon thread was passed into the bladder and ignored. Besides, in finger assisted technic, all studied patients were satisfied with the treatment. In the latter group, leakage was appeared mildly in those with high body mass index by decreasing body weight. Two patients also experienced urinary retention that was disappeared after 3 days of CIC. Conclusion: Finger-assisted laparoscopic technic is accompanied with lower relapse and higher rate of symptoms removing; thus this technic is preferred to conventional method in management of SUI.

Background and Objective: Although urolithiasis is not common in pregnancy, but is the most common nonobstetric complication in pregnant women. It can associate with significant potential risks for both mother and fetus and needs multi-disciplinary and perfect team work. Diagnosis and management are challenging because of physiological changes and limitation of radiation exposure during pregnancy. Material and Methods: 80 articles that discussed about consensus and controversies of the urolithiasis in pregnancy were extracted from PubMed and Medline. Results: Ultrasound is the first choice as a diagnostic imaging tool, but if not conclusive other options should be considered. Fortunately, conservative management is successful in most of cases, but if failed temporary or definite management may help the patient. However, percutaneous nephrostomy and stent insertion are considered as standard and classic methods, ureteroscopy and endoscopic lithotripsy also seems safe in special situations. Extracorporeal shock wave lithotripsy is contraindicated during pregnancy and percutaneous nephrolithotomy also is not recommended. Conclusion: To manage such situation a team work approach is needed involving the patient, urologist, radiologist, anesthesiologist and obstetrician so to achieve the best results and the least risks for mother and fetus.

Background and Objective: Renal stone disease is one of the most common problems in urology field. This cross-sectional study was done to determinate the causes of recurrent urinary stone disease in Hamadan city. Methods: All patients with recurrent renal stones who referred for treatment or follow up to nephrology and urology centers, participated in study and were compared with a control group. We filled demographic check list and did physical examination, and some plasma and urine laboratory tests were requested. For data analysis descriptive statistical test, t-test, Chisquare-Fischer test were used. Results: Data analysis showed that 46. 9 percent of cases had positive familial history of renal stone disease. Independent T-test showed significant differences between some of predisposing factors when it was used for comparing cases and controls. Results were P=0. 035, 0. 0001, 0. 012 for 24 hour urine calcium, uric acid and oxalate, respectively and P=0. 005 for both serum calcium and phosphate. Conclusion: There were basic factors of recurrent renal stone disease such as hypercalciuria, hyperuricosuria, hypocitraturia, hyperoxaluria, elevated serum iPTH, hypercalcemia, and hypophosphatemia in high percent of participants that each of them can be a separate factor to form and recurrence of renal stone in patients.

Background and aim: We report a case of endometriosis of the bladder diverticulum that was created after cesarean section. Case Report: A 45-year-old woman was diagnosed with abdominal pain during menstruation and hematuria after cesarean section. Pelvic tests and pelvic ultrasonography are normal in non-menstrual days. However, the last pelvic ultrasound showed a solid 9 × 6 mm anterior mass that adheres to the posterior wall of the bladder during menstruation. During a menstrual period, a cystoscope showed a 1-centimeter bulging nodular mass in a posterior wall diverticulum. Histologic diagnosis of endometriosis was in the bladder diverticulum wall. Conclusion: The post-operative period was not a problem and the clinical symptoms were completely resolved after removing the endometriosis of the bladder diverticulum.