Validity of P504S Staining for Diagnosis of Prostate Cancer

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AMIRZARGAR MOHAMMAD ALI; JAFARI MOHAMMAD; Kiani Alidad; Roshanaei Ghodratolah; Rasoli Jamkhaneh Seyed Jaber; Seif Panahi Hazhir; Rostaei Mahzad

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Journal: JOURNAL OF RESEARCH IN UROLOGY Year:2018 | Volume:2 | Issue:2 Page(s): 1-6

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Title

Validity of P504S Staining for Diagnosis of Prostate Cancer

Author(s)

Keywords

Immunohistochemistry

P504S

Prostate cancer

Abstract

Background and aim: The distinction between benign and malignant prostate lesions is one of the important issues in pathology. Misdiagnosis in these cases can lead to unnecessary treatments. The purpose of this study was to evaluate the diagnostic value of P504S sputum penetration in diagnosis of Prostate cancer. Material and Methods: In this experimental study, 33 benign samples and 33 prostate malignant samples from needle biopsy were selected by available sampling method and the immunohistochemical marker P504S was determined. Following the pathology diagnostic method as a standard, the immunohistochemical marker P504S of benign cases was compared to malignant ones (P<0. 05). Results: Comparing the results of two methods of P504S staining and pathologic methods showed that there is a significant relationship between these two methods in the diagnosis of prostate malignancies. (P=0. 0001). Also, considering the pathologic diagnosis as the standard Gold method for diagnosis of prostate malignancies, all four sensitivity, specificity, positive predictive value and negative predictive value for P504S staining method in diagnosis of prostate malignancies was 97%. Conclusion: The findings of this study showed that this coloration has high sensitivity, specificity and high predictive value in evaluating the value of diagnosis of P504S staining method in diagnosis of Prostate cancer. Therefore it can be used with high confidence in the differentiation of benign prostatic malignant lesions in diagnostic laboratories.

Cites

Prostate cancer with a large cystic lesion (Case Report)

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APA: Copy

AMIRZARGAR, MOHAMMAD ALI, JAFARI, MOHAMMAD, Kiani, Alidad, Roshanaei, Ghodratolah, Rasoli Jamkhaneh, Seyed Jaber, Seif Panahi, Hazhir, & Rostaei, Mahzad. (2018). Validity of P504S Staining for Diagnosis of Prostate Cancer. JOURNAL OF RESEARCH IN UROLOGY, 2(2 ), 1-6. SID. https://sid.ir/paper/267654/en

Vancouver: Copy

AMIRZARGAR MOHAMMAD ALI, JAFARI MOHAMMAD, Kiani Alidad, Roshanaei Ghodratolah, Rasoli Jamkhaneh Seyed Jaber, Seif Panahi Hazhir, Rostaei Mahzad. Validity of P504S Staining for Diagnosis of Prostate Cancer. JOURNAL OF RESEARCH IN UROLOGY[Internet]. 2018;2(2 ):1-6. Available from: https://sid.ir/paper/267654/en

IEEE: Copy

MOHAMMAD ALI AMIRZARGAR, MOHAMMAD JAFARI, Alidad Kiani, Ghodratolah Roshanaei, Seyed Jaber Rasoli Jamkhaneh, Hazhir Seif Panahi, and Mahzad Rostaei, “Validity of P504S Staining for Diagnosis of Prostate Cancer,” JOURNAL OF RESEARCH IN UROLOGY, vol. 2, no. 2 , pp. 1–6, 2018, [Online]. Available: https://sid.ir/paper/267654/en

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