Due to the increasing evidence of hirsutism among Iranian women, the present study was conducted at Tarbiat Modarress university specialty clinic for a period of 18 months to examine the different aspects of this disease.One hundred and seventy five patients were studied. A medical history and physical examination were obtained in each case, after determining a score according to the ferriman and Gallwey method, the following tests were performed on the 21 st day of the menstrual cycle: ACTH, CORTISOL, FSH, LH, OESTRADIOL, 170 HP, PROGESTERONE, T3, T4, TSH, TESTOSTERONE, SHBG, ANDROSTANDJONE, PROLACTIN and DHEA.S.The result showed that in 14.9 % of the cases, hyperprolactinemia was associated with hirsutism.Prolactin had a serum prolactin above 20 ng/ml. Androgen changes in hirsut women with hyperprolactinemia were as Fallows: an increase in DHEAS, Testosterone and ADD in 35% and 20% and 11/1% of the cases, respectively.The mean prolactin level in hyprolactinemic hirsut women was found to be 31 ng/ml, and in other hirsut women, 10.8 ng/ml.Index TEST / SHBG in hyperprolactinemic hirsut women were higher than other hirsut women.The mean hormans: SHBG and progesterone in hyperprolactinemic hirsut women were lower than other hirsut women.In conclusion in order to evaluate hirsut women, it is necessary to periodically measure prolactin.