background and objective: The present paper aims to study the relationship between management styles and organizational effectiveness in exceptional talents office of the universities of medical sciences all over the country.methods: The present study is a descriptive correlational study. The statistical population includes all managers and personnel of the exceptional talents office of the universities of medical sciences all over the country for 250 among whom the number of 150 ones has been selected as sample base on Cochran’s formula. Accordingly for data collection, Likert leadership style questionnaire and Parsons organizational effectiveness model are applied. After data gathered, they are analyzed by Pearson Correlation Coefficient, Independent t test, Regression analysis and SPSS software.results: The results show that the research main hypothesis, the management styles and organizational effectiveness in exceptional talents office of the universities of medical sciences all over the country have a significant relationship (r=0.47, P=0.000). Based on other research results, the highest correlation grade is for participatory management and it is determined that there is a significant and direct relationship between participatory management style and organizational effectiveness, (r=0.47), moreover, there is a significanr relationship between charity style (r=0.41) and consultative style (r=0.44) with organizational effectiveness. However, there was no significant relationship between despotic management style and organizational effectiveness.. Also, the findings show that 68 people used participatory management style, 47 ones used autocratic management style and the rest used advisory and benevolent styles.conclusion: Based on the findings of study, it can be concluded that the use of participatory style in educational organizations such as universities is necessary.