Background: If we accept the teaching activity is purposeful and its aim is to promote learning of persons so it must have a planned. Today, with the advancement of science in medical universities Using participatory methods and problem-based, student-centered had emphasizes. According to many experts, roleplaying teaching method is a method By placing Persons at the simulated environments Caused Promote learning process, critical thinking and active involvement of the learner-with the teaching and interaction between teacher and student. In this paper we discuss various aspects of role playing teaching methods in various articles and trying to keep up with in-depth review of literature pay The requirements of this teaching method in medical universities.Methods: In this study, by using the key words role playing, medical education, medical universities, teaching methods and, articles were selected related studies from 1995 to 2014 Google scholar, pub med, Scopus databases and local and foreign journals were related to medical education, Based on the posed in This fields of education, the situation in this method were studied in different universities of medical sciences and finally 36 were studied.Results: The Research about the teaching method showed the teaching methods are integrated with-learning strategies such as problem-based learning and collaborative and more to the use of this method for-teaching affective domain has been changed therefore necessary that faculty become familiar with learning-strategies. Studies the positive effects of the teaching role playing methods clinical and theoretical medical education are supported.Conclusion: Improving learning and teaching process need to use different methods and combine multiple methods in teaching. Based on the studies reviewed recommended teachers to teach various skills in cognitive and functional domains used of these teaching methods.