Introduction: Self-care is an important element of the health life style and has an important place in Islamic medicine. Islam, as the most comprehensive divine religion, has a system of integrated care in the field of health which is based on self-care. Islam While emphasizing on the empowering the people in hygiene and disease prevention, is mainly intended to instill a belief in self-care and on this basis, has provided several recommendations to strengthen self-care behaviors that to review and classify them can be an effective strategy in this field. This study aimed at outlining and explaining the care system in Islam and the extraction and classification of self-care strategies to strengthen the health sector, in the verses and Islamic traditions.Methods: This research is done by studying the Quran and Islamic traditions. In the first, “The Encyclopedia of Medical traditions” by Ayatollah “Mohammadi Rey shahri”, were reviewed and then the traditions was selected accordance to the research goals.Findings: Early based on Quranic verses and Islamic traditions, self-care system in Islam explained and then, four strategies to strengthen self-care behaviors were presented in the Qur’an and Hadith; They include: Delineate Islamic lifestyle, The strengthening of the religious beliefs in health, Awareness and information, Empowerment and Skill synergy.Conclusion: Islam has an integrated system of self-care in health and to strengthen self-care behavior in different ways offers. Understanding these strategies, it will help the authorities to strengthen the religious beliefs of individuals and implement these strategies to promote the culture of self-care in the community.