THE ROLE OF PROBIOTICS IN COLON CANCER PREVENTION

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KARAM AMAN MOHAMMAD; EBRAHIMI SHARIF; MOHAMMADI REZA; MORTAZAVIAN AMIR MOHAMMAD; SADEGHI EHSAN; ROUHI MILAD; SHADNOUSH MEHDI

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Journal: Medicine and Spiritual Cultivation Year:2015 | Volume:24 | Issue:2 Page(s): 29-42

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Title

THE ROLE OF PROBIOTICS IN COLON CANCER PREVENTION

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Keywords

PROBIOTICSQ2

NEOPLASMSQ2

PREVENTIONQ3

COLORECTALQ3

Abstract

Backgrounds: Colon cancer is the most important cancer around the world and the colonic microflora and Diet makes an important contribution to cancer. This has led to intense interest in factors such as PROBIOTICS that can modulate gut microflora and its metabolism.Methods: In review article were collected by searching in informative bank such as www.isi web of knowledge.com, www.Scincedirect.com and www.scopus.com between 1995 to 2012.The keywords PROBIOTICS, NEOPLASMS (Cancer), Lactobacillus and Bifidobacreium were used for searching.Findings: The strongest evidence for the anticancer effects of PROBIOTICS comes from animal studies, and evidence from human studies (epidemiology and experimental) is still limited. There are several possible mechanisms that might explain how probiotic bacteria might protect against tumor development in the colon. However, questions such as what is the major contributing mechanism for a particular bacterial strain, or how are the different mechanisms linked are questions to which we currently do not have the answers. It is possible that different strains target different mechanisms. All of the mechanisms have various degrees of support, mainly originating from in vitro and animal experiments, and some of them even have some support from human clinical studies.Conclusion: More research needs to be done to identify the specific strains and strain characteristics responsible for specific antitumor effects and the mechanisms by which these effects are mediated. More clinical trials are needed to better understand the exact underlying mechanisms, and to strengthen the suggestions that PROBIOTICS could play a major role in preventing colonic cancers.

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APA: Copy

KARAM, AMAN MOHAMMAD, EBRAHIMI, SHARIF, MOHAMMADI, REZA, MORTAZAVIAN, AMIR MOHAMMAD, SADEGHI, EHSAN, ROUHI, MILAD, & SHADNOUSH, MEHDI. (2015). THE ROLE OF PROBIOTICS IN COLON CANCER PREVENTION. TEB VA TAZKIEH, 24(2), 29-42. SID. https://sid.ir/paper/34486/en

Vancouver: Copy

KARAM AMAN MOHAMMAD, EBRAHIMI SHARIF, MOHAMMADI REZA, MORTAZAVIAN AMIR MOHAMMAD, SADEGHI EHSAN, ROUHI MILAD, SHADNOUSH MEHDI. THE ROLE OF PROBIOTICS IN COLON CANCER PREVENTION. TEB VA TAZKIEH[Internet]. 2015;24(2):29-42. Available from: https://sid.ir/paper/34486/en

IEEE: Copy

AMAN MOHAMMAD KARAM, SHARIF EBRAHIMI, REZA MOHAMMADI, AMIR MOHAMMAD MORTAZAVIAN, EHSAN SADEGHI, MILAD ROUHI, and MEHDI SHADNOUSH, “THE ROLE OF PROBIOTICS IN COLON CANCER PREVENTION,” TEB VA TAZKIEH, vol. 24, no. 2, pp. 29–42, 2015, [Online]. Available: https://sid.ir/paper/34486/en

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