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مرکز اطلاعات علمی SID1
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    300
  • Downloads: 

    349
Abstract: 

Introduction: amnesia is one of the most important goals in General Anesthasia. From the point of Psychological views, Awareness in general Anesthesia is not desirable, and elimination of it, is necessary. Overiall 1% of all patients have awareness and it maybe 10% in some anesthesia techniques. There is not a precise statiscal survey about awareness in NLA. This study attempts to present a statiscal work. Methods: All of the 60 patients in this study were 20-45 years old, under spinal surgery and in class I-ASA. All of them have been taken 10 mg of Diazepam over the night before operation and 7ml/kg of Ringer solution has been administered in the operating room. (Group A): Neurolept anesthesia started with induction (Talamonale 0.1 ml/kg, Thiopental 5 mg/kg, Pancuronium 0.1 mg/kg), maintained with N2O-Fentanyl (50 µg/30 min).(Group B): Induction with (Fentanyl 1.5 µg Thiopenthal 5 mg/kg, Pancuroniom 0.1 mg/kg) and maintanence with (Halothane 0.6%, N2O, Fentanyl 50 µg/30 min) was administerd.Atype player was used during G.A. Patients were requested answer the questions in recovery room and 24 hour after anesthesia. Results: According to Z test, there is no significant difference in awareness between the tow groups studied. Also according to X2test, there is no significant difference in awareness between the tow groups studied. All cases of awareness were in 35-45 years of agr. Conclusion: In NLA the voice heard by the patient is not percieved unpleasant. According to results, awareness in NLA was not more comparred to the other anesthesia techniques. So NLA can be used as a safe technique with more advantage in Poor Risk patients and who needs wake up test during surgery.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    238
  • Downloads: 

    349
Abstract: 

History and objectives: Intracranial hemorrhage (I.C.H) is an important cause of mortality and neurologic sequels in the neonatal period. As there is little information about the prevalence and etiologies of neonatal I.C.H. in Kashan this study was carried out on admitted newborns in Kashan hospitals during 1375-1379. Material and Methods: This retrospective descriptive study was conducted on 2755 neonates. After confieming I.C.H. in affected neonates the data about gestational age, sex, clinical symptoms, mode of delivery, maternal risk factor, type and cause of hemorrhage were collected from medical records and results were analysed. Results: Of 62 cases of I.C.H. 42 were in preterm and 20 were in fullterm neonates.The most common etiology of I.C.H. in preterm and Term neonate was asphyxia and trauma respectively. The most common type of I.C.H. in preterm was intraventricular hemorrhage versus subdural hemorrhage in full terms. There was no significant relationship between I.C.H and sex and mode of delivery. Decreased More reflex was the most common clinical finding and preeclampsia was the most important maternal risk factor in I.C.H. Conclusion: Considering the frequency of I.C.H in preterm neonates (27 times more than full terms neonates) and asphyxia as the most common etiology, significant efforts should be performed to prevent preterm deliveries and occurrence of asphyxia.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    230
  • Downloads: 

    349
Abstract: 

Background: Intracranial hemorrhage (ICH) is an important cause of mortality and neurologic sequels in the neonatal period. As there is little information about the prevalence and etiologies of neonatal I.C.H. in Kashan, the present study was carried out on neonates admitted in Kashan hospitals during a 4-year period, 1996-2000. Material and methods: This retrospective study was conducted on 2755 neonates. Having the diagnosis confirmed, initial data including gestational age, sex, clinical manifestations, mode of delivery, maternal risk factors, type and cause of hemorrhage were collected from medical records and results were analyzed. Results: Of 62 cases of ICH, 42 were in preterm and 20 were in full term neonates. The most common etiology of ICH in preterm and term neonate was asphyxia and trauma, respectively. The most common type of ICH in preterm was intraventricular hemorrhage versus subdural hemorrhage in full terms. There was no significant relationship between ICH and sex or mode of delivery. Decreased More reflex was the most common clinical finding and preeclampsia was the most important maternal risk factor in ICH. Conclusion: Considering the frequency of ICH in preterm neonates (27 times more than full terms neonates) and asphyxia as the most common etiology, further attempts should be employed to prevent preterm deliveries and occurrence of asphyxia.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    205
  • Downloads: 

    349
Abstract: 

Background: General anesthesia could be accompanied by changes in hemodynamic parameters (arterial blood pressure, heart rate, rhythm, central venous pressure, and venous blood pressure) that would result in altered intracranial pressure. In deep anesthesia the brain perfusion is dependent on blood pressure. The present study was conducted to determine the effects of neurosurgery on hemodynamic parameters in Naghavi Hospital in Kashan. Materials and methods: This quasi-experimental study was performed on 112 patients. Systolic and diastolic blood pressure, and cardiac rhythm and rate were measured. Then the influence of sex, age, type of operation, duration of surgery and patients position on aforementioned parameters were evaluated. Results: The study population included 70 males and 42 females, most of whom aged ≥40 years. Hemodynamic changes were more apparent among males. Meanwhile, age of ≥40 years, spinal surgery, prone position, and operations of more than 2-hour duration were associated with greater hemodynamic changes. Changes in systolic and diastolic blood pressure during induction was significantly differed regarding the duration of operation and patients position. Conclusion: Hemodynamic changes are common in neurosurgical operations. These are different according to the type and duration of surgery and patients position. Further studies are highly recommended.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    236
  • Downloads: 

    349
Abstract: 

Background: Evaluating the process of childs growth monitoring is of utmost importance to detect malnourishment. The present study was conducted with the aim of determining the trend of infant growth from birth to 2 years in the rural community of Babol and compare this with NCHS. Materials and methods: This exiting data type study was conducted on monitoring growth system in Babol rural communities, which were covered by health centers. 429 children with their birth between 1994 to 1996 were selected through a cluster sampling technique. The percentiles of height and weight were calculated and compared with NCHS standard. Results: Results have revealed that the weight of 67.5% of infants was between 50th and 97th NCHS standard at 1 month. This figure was reduced by increasing the age to 45.2% at 6 month, 42.6% at 12 month and 44.2% at 24 month. Girls growth profile showed a 5-20% reduction as compared to boys. Results also showed that the reduction of height in comparison with standard, was began at age 1 to 3 month. The 50th percentile of height was close to the NCHS, but after 3 month it deviates from NCHS. A significant difference was observed between 50th percentiles of height and weight with NCHS (p< 0.05). Conclusion: The results indicated that Iranian infants growth can not be evaluated with NCHS standard. It is necessary to provide national and local charts of the growth for Iranian children.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    244
  • Downloads: 

    349
Abstract: 

Background: Consanguineous marriage is one of the most important etiology of morbidity and anomaly in neonates and children, for which annually thousands of neonates and children sacrifice. This study was performed in Shabihkhani hospital in Kashan to determine the prevalence of congenital anomalies among consanguineous marriages. Material and methods: All neonates born in Shabihkhani hospital in 2000-01 were included and initial data including sex, gestational age, type of delivery, prenatal care, drug history, special disease in mother, type of anomaly, history of still birth or anomaly in previous pregnancy were recorded. Type of anomaly in the first 24 hours was distinguished for further classification. Paraclinic tests and consultations were also used. Results: Of 3529 neonates, 768 (21/8%) were born of a consanguineous marriage and the remaining 2761 (78.2%) from non-consanguineous marriage. Totally, 109(3.08%) deliveries were led to neonates anomaly, of these 7.03% were in the consanguineous marriage group (72.3% in first-cousin marriage and 27.7% in second-cousin marriage) and 2% in the other group. Conclusion: The prevalence of consanguineous marriage in our study was relatively high and the rate of neonate anomaly of consanguineous marriage was more than what expected. Obviously, in case of consanguineous marriage, the rate of anomaly clearly increased.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    244
  • Downloads: 

    349
Abstract: 

Background: The evaluation of the monitoring growth of children is one of the important source of information to detect malnutrishment. The objective of this study was to etermine the trend of infant growth from birth to 2 years in the rural community of Babol and to compare it with NCHS. Methods: This study was conducted based on the exiting data in the monitoring growth system in Babol communities which were covered by health centre. A sample of 429 children with their birth between 1994 to 1996 were selected using cluster sampling techniques. The precentiles of height and weight were calculated and they were compared with NCHS standard. Results: The results shows that the weight of 67.5% of infants was between 50th and 97th NCHS standard at 1 month. This figure was reduced by increasing the age to 45.2% at 6 month, 42.6% at 12 month and 44.2% at 24 month. When these figures were compared among boys and girls, the above rates 5% to 20% were less among girls than boys. The results also shows that the 50th precentile of NCHS standard, but after that it was lower than NCHS. The reduction of height in compared with standard was began at age 1 to 3 month. The 50th precentile of height was close to the NCHS, but after 3 month it deviates from NCHS. A significant difference was observed between 50th precentiles of height and weight with NCHS (P < 0.05). Conclusion: The results indicated that Iranian infant growth can not be evaluated with NCHS standard. It is neseccary to provide national and local charts of the growth for Iranian children.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    384
  • Downloads: 

    349
Abstract: 

Background: Cephalosporin C (CPC), as a major precursor of semisynthetic cephalosporin antibiotics, is produced by species of acromonium genus in certain conditions. Thus the present study was carried out to isolate and obtain the strains and detecting their production as well as defining optimum production and purification conditions. Materials and methods: During this exploratory study, selective media were used for soil screening program. Standard strains were purchased from DSMZ (Germany). CPC production was confirmed by biological and chromatographic (paper chromatography and HPLC) techniques. To produce induction, different kinds of media with various carbon and nitrogen sources were used. CPC were removed from filtered and acid-treated broth by absorption on a neutral macroporous resin (XAD-4), followed by absorption on a weakly basic ion-exchange resin (IRA-67). Results: In soil screening program, a native CPC-producing strain was isolated. CPC production of this strain and also of standard strains was confirmed by other methods. Native and standard strains were differed in CPC production in various fermentation media. CPC was recovered and extracted from these media with acceptable purity. Conclusion: Results have implied that this product can be used for large-scale production of CPC in our country

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    293
  • Downloads: 

    349
Abstract: 

Background: Awareness is a common problem of general anesthesia. The overall prevalence of awareness was reported 1-10%. The present study was conducted to determine the effects of neurolept anesthesia on awareness. Materials and methods: This double blind clinical trial was performed on sixty 25-40-year old individuals undertaking spinal surgery. All of whom belonged to class I-ASA. Patients received 10 mg of Diazepam over the night before operation and 7ml/kg of ringer solution was administered in the operating room. For the first group (Group A) neurolept anesthesia started with induction (talamonale 0.1ml/kg, thiopental 5mg/kg, and pancuronium 0.1mg/kg), maintained with N2O-fentanyl (50µg/30 min). For the second group (Group B) induction was started with fentanyl 1.5µg/kg, thiopenthal 5mg/kg, pancuronioum 0.1mg/kg) and maintained with halothane 0.6%, N2O-fentanyl 50µg/30 min. A tape player was used during the procedure and patients awareness was measured using the pain sensation and music recall following the procedure in recovery room and 24 hour after anesthesia. Results: Voice was heard by 10 and 3.3% of patients in the neurolept and control group, respectively (NS). Type of anesthesia had no effect on blood pressure and heart rate. Conclusion: Neurolept anesthesia accompanied by minor changes in patients awareness, thus this can be safely used as a safe technique with more advantage in poor risk patients and those who need wake up test during surgery.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    253
  • Downloads: 

    349
Abstract: 

Background: Vasectomy is one of the most effective tools of population control. Controversies are arisen with respect to the effects of vasectomy on testis and the process of spermatogenesis, thus the present study was carried out to determine the effects of closed-end and open-end vasectomies on rats testis in Kashan University in 2000. Materials and methods: For this experimental study, 20 Sprague Dawely rats were randomly selected. They were 8-12 weeks old and assigned in two groups of closed-end and open-end vasectomies. For the first group (closed-end) right vas deferens underwent closed-end operation and vas deferens of the left side underwent Sham operation, however for the other group (open-end) right and left vas deferens underwent open-end and Sham operations, respectively. 4 months later, their testes were removed and their weight, volume and macroscopic appearance were determined. Then, microscopic changes including histologic changes, seminoferous ducts, interstitial tissue, number of spermatogonia, number and type of spermatocytes, etc were all recorded. T-test was used for data analysis. Results: Histologic studies revealed that testicular tissue was normal in control group but have changes in the case group. In injured ducts detachment of immature cells from epithelium, epithelial vacuolization, thickening and folding of periductal membrane, and removal of germ cells were prominent changes. Quantitative evaluation of normal ducts revealed that there was significant differences between groups regarding: number of spermatogonia, spermatocyte, round spermatid, long spermatid, the proportion of long spermatid to sertoli, ductal diameter, and volume and weight of testis. Conclusion: There was no significant difference between the closed- and open-end vasectomies, however both affect the testicular tissue. Effects of increased hydrostatic pressure were less prominent in closed-end technique. Further studies with special attention on increased antisperm antibody , and seminoferous ductal structure wit0.h ultrastructure and immunochemistry are strongly suggested.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    213
  • Downloads: 

    349
Abstract: 

Background: Breast cancer is a common problem with known complications. The aim of this study is to determine the characteristics of women with breast complaint referring to Al-Zahra surgery clinic in Isfahan in 1999-2000. Materials and methods: 300 women with breast complaints had entered this descriptive study. Initial data including age, weight, age of marriage, age of menarche and menopause, family size, OCP taking, history of breast cancer in first degree relatives, persistence of mass, nipple discharge, etc were all recorded. Results: Mean age (±SD) of patients was 36.6±12.8 years, mean weight was 63.19±11.5 kg, mean age of marriage was 17.8±4.2. The mean age of menarche and menopause were 13.4±1.4 and 43±13.2 years, respectively. The vast majority of patients (96.7%) were unaware of self-examination. OCP was taken by 58%. 91.3% had nipple discharge, of whom 1.4% had bloody discharge. Conclusion: Results have revealed that the onset of breast complaints is relatively low in Isfahan, thus screening tests should be employed. Furthermore, educational programs, regarding self-examination, are highly recommended.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    255
  • Downloads: 

    349
Abstract: 

Background: Asbestosis, a disorder arising from fibrillar mineral compounds of hydrose silicat, damages lungs and causes respiratory signs. Asbestosis is a risk factor for pleural neoplasm, and tuberculosis has been proposed as a risk factor for progression of asbestosis and a complication in advanced asbestosis. We have surveyed the association between asbestos exposure and pulmonary tuberculosis in a group of Iranit factory workers in Tehran. Material and Methods: During this single-blind historical cohort study, 202 asbestos- exposed workers (case group) and 201 non-exposed workers (control group) were compared regarding the clinical and paraclinical studies, including CBC,ESR, PPD, CXR, sputum and BAL fluid smear and culture for mycobacterium tuberculosis. Results: Groups were matched according to the sex, age, duration of exposure and smoking habit. Of the case and control groups, 7 (3.5%) and 1 (0.5%) subjects were revealed to be infected by TB, respectively. Cumulative Incidence Risk (CIR) was 6.96 showing asbestos-exposure predisposes subjects to TB. Positive PPD of more than 15 mm in case and control groups was 14.4% and 21.9%, respectively. It means that asbestos-exposure decreases reactivity to PPD. (p< 0.05) Conclusion: Exposure to asbestos predisposes subjects to secondary tuberculosis, possibly by reactivation of dormant foci of TB in lung. So periodic examination of exposed subjects is strongly suggested and is indicated for early detection and management

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    252
  • Downloads: 

    359
Abstract: 

Background: With respect to the frequency of difficult intubation and its known complications, the present study was conducted in Matini hospital in Kashan to determine the value of predictive tests. Materials and methods: This descriptive study was carried out on 379 patients referring for surgery. During the first preoperation visit Mallampati test was achieved and patients were categorized in either I to IV classes. Then the thyromental distance was measured. Induction was managed by sodium thiopental 5mg/kg and succinile choline 1.5mg/kg, then laryngoscopic view was determined according to the Cormack classification. Those who were classified as grade III or IV in Mallampati test or had thyromental distance of less than 6cm were considered as at risk patients for intubation. Those who fell in Cormack III of IV classification were considered as difficult intubation. Finally, sensitivity, specificity, positive and negative predictive values of these tests were calculated. Results: The study population included 179 males and 200 females with the mean age of 45.1±22.4 years. Of 379 patients, 29 (7.7%) were revealed to have difficult intubation. Positive and negative predictive values of Mallampati test was 12% and 93%, respectively, however, these values were 9.8% and 92.7% for Thyromental test. Conclusion: With respect to the low sensitivity and PPV of Thyromental and Mallampati tests, they are of limited value for detection of difficult intubation.

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Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    1-10
Measures: 
  • Citations: 

    0
  • Views: 

    549
  • Downloads: 

    110
Abstract: 

سابقه و هدف: وازکتومی یکی از روش های مناسب جهت جلوگیری از بارداری و کنترل جمعیت است. با توجه به گزارشات ضد و نقیض در ارتباط با تاثیرات وازکتومی روی بافت بیضه و روند اسپرماتوژنزیس و اهمیت بررسی نقش عوامل ایجاد کننده تغییرات در بیضه، به منظور تعیین تاثیر دو تکنیک جراحی وازکتومی بسته و باز روی بافت بیضه و نقش افزایش فشار ئیدروستاتیک در ایجاد تغییرات، این تحقیق در سال 1379 در گروه علوم تشریح کاشان انجام گرفت. مواد و روش ها: در این تحقیق تجربی 20 سر رت نژاد Sprague Dawely در سنین 8 الی 12 هفتگی بطور تصادفی انتخاب و در دو گروه وازکتومی بسته و باز تقسیم شدند: در گروه وازکتومی بسته مجرای دفران راست آنها تحت عمل وازکتومی بسته و طرف چپ آنها تحت عمل Sham و در گروه وازکتومی باز که مجرای دفران راست آنها تحت عمل وازکتومی باز و طرف چپ آنها تحت عمل Sham قرار گرفت. بیضه موشها چهار ماه پس از عمل جراحی برداشته شد. وزن و حجم بیضه ها و تغییرات ظاهری آنها مشخص شد و پس از فیکس کردن، آماده سازی، برش گیری و رنگ آمیزی تحت میکروسکوپ نوری تغییرات بافتی و قطر مجاری منی ساز، درصد حجمی مجاری طبیعی و غیرطبیعی، درصد حجمی بافت بینابینی، تعداد سلولهای اسپرماتوگونیا، اسپرماتوسیت پاکی تن، اسپرماتید گرد، اسپرماتید بالغ سرتولی و نسبت اسپرماتید گرد به سلول سرتولی در گروه مورد و شاهد و همچنین بین دو روش جراحی وازکتومی تعیین گردید و با روش آماری t-test مورد مقایسه قرار گرفتند. یافته ها: بررسی هیستولوژیک نشان داد که بافت بیضه در گروههای شاهد ظاهر کاملا طبیعی دارند ولی بیضه گروههای مورد در هر دو روش تغییرات متفاوتی را نشان دادند. در مجاری آسیب دیده تغییراتی از جمله جدا شدن سلولهای نابالغ از اپی تلیوم، شکاف و ایجاد واکوئل در اپی تلیوم، چین خوردگی و ضخیم شدن غشای دور مجاری و حذف سلولهای جرم مشاهده گردید، بررسی کمی مجاری با ظاهر طبیعی نشان داد که تعداد سلولهای اسپرماتوگونیا، اسپرماتوسیت پاکی تن، اسپرماتید گرد، اسپرماتید طویل، نسبت اسپرماتید گرد به سرتولی، قطر مجاری، وزن و حجم بیضه بین گروه مورد و شاهد در هر دو روش جراحی اختلاف معنی داری وجود دارد. در بقیه متغیرها اختلاف معنی داری دیده نمی شود. مقایسه پارامترهای فوق از نظر دو روش جراحی هیچ اختلاف معنی داری را نشان ندادند. نتیجه گیری و توصیه ها: تغییرات ایجاد شده در بیضه های گروه وازکتومی بسته و باز اختلاف معنی داری ندارند و وازکتومی با انتهای باز و بسته روی بافت بیضه تاثیر می گذارد و نقش افزایش فشار ئیدروستاتیک در گروه وازکتومی بسته در ایجاد تغییرات کمتر بوده و پیشنهاد می گردد در آینده مطالعات گسترده تری در ارتباط با بررسی نقش عوامل دیگر از جمله افزایش تیتر آنتی بادی آنتی اسپرم در ایجاد تغییرات و ساختار غشای دور مجاری منی ساز از نظر اولترااستراکچر و ایمنوهیستوشیمی مورد بررسی دقیق قرار گیرد.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    11-15
Measures: 
  • Citations: 

    1
  • Views: 

    1590
  • Downloads: 

    381
Abstract: 

سابقه و هدف: یکی از مشکلات شایع بیهوشی، به یادآوردن خود به خودی حوادثی است که در زیر بیهوشی عمومی برای بیمار اتفاق می افتد. 1-10 درصد بیماران در شرایط گوناگون آگاهی زیر بیهوشی را تجربه می کنند، لذا به منظور تعیین تاثیر بیهوشی نورولپت بر میزان آگاهی، این تحقیق در بیمارستان مطهری شهر ارومیه در سال 1378 انجام گرفت. مواد و روشها: تحقیق به روش کارآزمایی بالینی دوسوکور بر روی 60 بیمار 20-45 ساله کاندید عمل جراحی ستون فقرات که از نظر فیزیکی در کلاس بیهوشی بودند و شب قبل از عمل 10 mg دیازپام دریافت کرده و روز عمل نیز با 7 میلی لیتر به ازای هر کیلوگرم وزن بدن سرم رینگر هیدراته شده بودند، انجام گرفت. در گروه بیهوشی نورولپت، القای بیهوشی با تالامونال (0.1 ml/kg)، تیوپنتال5 mg/kg، و پانکرونیوم 0.1 mg/kg و نگهداری بیهوشی با –N2O فنتانیل 50 μg/30 min انجام گرفت. در گروه شاهد، القای بیهوشی با فنتانیل1.5μg/kg) ، تیوپنتال 5mg/kg و پانکرونیوم 0.1Mg/kg و نگهداری با )هالوتان –N2O %0.6 فنتانیل (50 mg/30 min انجام گرفت. در طی بیهوشی موسیقی پخش می گردید و میزان آگاهی با شنیدن صدای موسیقی و تشخیص آن و نیز احساس درد، یکبار در اتاق مراقبتهای بعد بیهوشی (ریکاوری) و یک بار روز بعد، بررسی و ثبت گردید. یافته ها: تحقیق روی 60 بیمار در دو گروه 30 نفری انجام گرفت. میزان شنیدن صدا به تنهایی در گروه شاهد %3.3 و در گروه نورولپت (NS)%10 و شنیدن صدا توام با احساس درد به ترتیب صفر و 3.3 درصد بود (NS). نوع بیهوشی روی فشار خون و ضربان قلب تاثیر معنی داری نداشت. نتیجه گیری و توصیه ها: روش بیهوشی نورولپت تاثیری بر میزان آگاهی زیر بیهوشی ندارد و می تواند به عنوان یک تکنیک با مزایای فراوان در جراحی های مختلف و بیمارانی که نیاز به Wake up تست دارند، به کار برده شود.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    16-21
Measures: 
  • Citations: 

    0
  • Views: 

    1068
  • Downloads: 

    111
Abstract: 

سابقه و هدف: با توجه به حجم زیاد لوله گذاری مشکل و عوارض شناخته شده آن و نیز به علت تناقضاتی که در نتایج مطالعات قبلی در مورد ارزش تستهای پیش بینی کننده لوله گذاری مشکل وجود دارد، این مطالعه بر روی بیماران مراجعه کننده جهت عمل جراحی به بیمارستان متینی کاشان در سال 1377 انجام گرفت. مواد و روشها: پژوهش بصورت توصیفی بر روی 379 بیمار مراجعه کننده به بیمارستان انجام گردید. در ویزیت قبل از عمل، ابتدا تست مالامپاتی صورت می گرفت و بیمار در یکی از درجات I تا IV این طبقه بندی قرار داده می شد. سپس فاصله تیرومنتال (فاصله بین برجستگی تیرویید تا چانه وقتی که سر اکستانسیون کامل دارد) بوسیله خط کش اندازه گیری و ثبت می گردید. پس از القا بیهوشی با تیوپنتال سدیم به میزان 5mg/kg و سوکسنیل کولین 1.5 mg/kg و اکسیژناسیون بیمار، لارنگوسکوپی صورت می گرفت و منظره لارنگوسکوپیک بر اساس طبقه بندی Cormack بعنوان روش تشخیصی مثبت ثبت می گردید. بیمارانی که در درجات III و IV مالامپاتی قرار می گرفتند یا فاصله تیرومنتال آنها کمتر از 6 سانتیمتر بود به عنوان بیماران در معرض خطر ((لوله گذاری مشکل)) در نظر گرفته می شد و بیمارانی که منظره لارنگوسکوپیک آنها در درجات 3 و 4 کورمک قرار می گرفت، تحت عنوان موارد لوله گذاری مشکل تلقی می گردیدند. در پایان، حساسیت، ویژگی، ارزش اخباری مثبت و منفی این تستها در تشخیص موارد لوله گذاری مشکل محاسبه گردیدند. یافته ها: از 379 بیمار مورد بررسی در این پژوهش %47.2 مرد و 52.8 زن بودند که میانگین سنی آنها 45.1 ±221.4 سال بود. در 29 بیمار (%7.7) لوله گذاری مشکل وجود داشت، ارزش پیش بینی مثبت تست مالامپاتی %12 و ارزش پیش بینی منفی آن %93.3 و در روش تیرومنتال به ترتیب %8.9 و %92.7 بود. نتیجه گیری و توصیه ها: به علت پایین بودن حساسیت و ارزش پیش بینی مثبت تستهای مالامپاتی و تیرومنتال، این تست ها در پیش بینی لوله گذاری مشکل ارزش محدودی دارند.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    1006
  • Downloads: 

    492
Abstract: 

History and objectives: The mechanism of growth hormone (GH) effects on growth plate (GP)and its chondrocytes is very important, so, in this study the microstructural of proximal tibial GP of rabbits were investigated with designed-based stereological methods by conventional light and confocal epifluorescence microscopy. Material and Methods: The tissue came from a study into longitudinalgrowth using minipomps surgically implanted into the right upper tibial GP of 9 weeks old rabbits, administering GH at 10 and 100 µg/day for a period of 21 days. Saline only administered and non operated groups served as controls. The following stereological parameters were unbiasedly estimated: GP volume and height; chondrocyte volume, surface and number densities. These direct measurements lead to estimates of chondrocyte total volume, surfaceand number; mean chondrocyte volume and surface in the number-weighted distribution. Right and left effects were compared using the paired sample t-Test. Dosage versus control were compared by initially performing single factor ANOVA, then if there was any significant difference, Dunnett,s multiple comparison test was performed. Results: No significant differences were found between the right and left tibial and salhne and control groups in the total quantities. The GP volume and height and chondrocyte total volume showed no significant differences between the treatment and control groups. Conclusions: The main conclusions were that the GH acts on rabbit proximal tibial GP by inducing chondrocyte hyperplasia but not hypertrophy . At the administered doses of GH, namely 10 and 100 µg/day, the predominant effects were mediated systemically. The operative procedure of implanting a minipomp had no detectable effect on any of the parameters measured. GH had an effect on the local cytostructure of the GP on the treated side. At the administered doses of GH no convincing overall does response was demonstrated. 1) Shahrod Faculty of Medical Sciences, Shahrood, IRAN. 2) Dept. of Pathology, Liverpool University, UK. Consanguineous marriage is one of the most important etiology of morbidity and anomaly in neonates and children and annualy thousands neonate and child sacrify due to consonguineous marriage. This study was performed shabihkhani hospital in Kashan. Material and Methods: All the neonates who were borned in hospital (shabihkhani) in this descriptive study were determined then these questions were ordered (sex, gestational age, type of delivery, perinatal care, drug history, special disease in mother, type of anomaly, history of still birth or anomaly in previous pregnancy). Type of anomaly in first 24 hours was distinguished for further classification paraclinic tests and consultations were used. Results: In this study from the total of 3529 neonate in one year, 768 (21/8%) were from consanguineous marriage and 2761 (78.2%) from nonconsanguineous marriage of them total pregnancies 109 (3.08%) had anomaly and 7.03% from consanguineous and 2% from nonconsanguineous and from all of the anomaly in consanguineous marriage 72.3% had in first. Cousin marriage and 27.7% had in second cousin marriage. Conclusion: Percentage of consanguineous marriage in our study was prominet and rate of anomaly in neonates of consanguineous marriage obviously was more than expected and in situations with relative marriage happened rate of anomaly clearly increased more and in these marriage major anomaly were predominant.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    31-36
Measures: 
  • Citations: 

    1
  • Views: 

    613
  • Downloads: 

    118
Abstract: 

سابقه و هدف: با توجه به شیوع بالای عفونتهای استافیلوکوکی و اهمیت مقاومت دارویی ناشی از آنها، این مطالعه به منظور تعیین الگوی مقاومت آنتی بیوتیکی سویه ها استافیلوکوکوس اورئوس جدا شده نمونه های کلینیکی ارسالی به آزمایشگاه مرکزی کاشان در نیمه اول سال 1377 انجام پذیرفت.مواد و روشها: این مطالعه به روش توصیفی بر روی 76 بیمار مراجعه کننده به آزمایشگاه مرکزی کاشان که در کشت ارسالی آنها استافیلوکوکوس اورئوس رشد کرده بود، انجام شد. نمونه های ارسالی بر روی محیطهای اختصاصی کشت داده شدند و تعیین هویت سویه ها، از طریق تست های اختصاصی انجام شد. سپس تعیین مقاومت آنتی بیوتیکی سویه های جدا شده، به روش انتشار دیسک در برابر آنتی بیوتیکهای مربوطه در محیط مخصوص آنتی بیوگرام انجام گرفت و اطلاعات به دست آمده به روش آمار توصیفی ارایه شد.یافته ها: از 76 نمونه بررسی، بیشترین میزان مقاومت آنتی بیوتیکی به ترتیب نسبت به اگزاسیلین (%96.1)، کلوگزاسیلین (%63.2)، سفالوتین (%23.7) و انکومایسین (%18.4) به دست آمد.نتیجه گیری و توصیه ها: میزان مقاومت استافیلوکوکوس اورئوس نسبت به اگزاسیلین و کلوگزاسیلین در کاشان بالاست. مطالعات تحلیلی برای تعیین ارتباط دقیق هر یک از داروها و قضاوت آماری در مورد آنها با توجه به نقش عوامل درمانی قبلی، سن، جنس و نوع رژیم دارویی توصیه می شود.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    37-42
Measures: 
  • Citations: 

    0
  • Views: 

    1637
  • Downloads: 

    258
Abstract: 

سابقه و هدف: با توجه به اینکه در جریان بیهوشی عمومی بیماران تحت اعمال جراحی مغز و اعصاب، تغییر در معیارهای همودینامیک بدن (فشارخون شریانی، تعداد ضربان قلب، ریتم قلب، فشار ورید مرکزی و فشار- شریان ریوی) می تواند سطح فشار داخل جمجمه و بالطبع وضعیت ساختمانهای داخل جمجمه را تغییر دهد و در بیهوشی های عمیق جریان خون مغزی وابسته به فشار، لذا با هدف تعیین میزان این تغییرات، پژوهش حاضر در اتاق عمل بیمارستان نقوی کاشان از دیماه 1377 تا خرداد 1378 انجام گرفت. مواد و روشها: پژوهش حاضر به روش نیمه تجربی بر روی 112 بیمار انجام پذیرفت که پس از معاینات فیزیکی توسط متخصصین جراحی مغز و اعصاب و بیهوشی، معیارهای (فشار خون سیستولی و دیاستولی، تعداد و ریتم ضربان قلب توسط دستگاه مانیتورینگ الکتروکاردیوگرام و کاف فشارسنج بازویی بررسی و نقش عواملی نظیر سن، جنس، نوع عمل، مدت جراحی و وضعیت حین عمل در تغییر پارامترهای فوق تعیین گردید. یافته ها: از مجموع 112 بیمار مورد بررسی، 70 نفر مرد (%62.5) و 42 نفر زن (%37.5) بودند. بیشترین فراوانی در رده سنی بالای 40 سال بود. مقادیر تغییرات همودینامیک در مردان بیشتر از زنان مشاهده شد و معیارهای فوق در رده سنی بالای 40 سال و جراحیهای روی ستون فقرات و در پوزیشن دمر و نیز اعمال جراحی طولانی تر از دو ساعت تغییر قابل توجه تری نشان داد. نتایج آزمونها نشان داد که تغییرات در فشار خون سیستولیک و دیاستولیک حین القا بیهوشی نسبت به قبل از آن نظر طول مدت عمل و پوزیشن حین جراحی و نیز تغییر در ضربان قلب حین القا بیهوشی نسبت به قبل از آن بر حسب جنس دارای اختلاف معنی داری است. نتیجه گیری و توصیه ها: تغییر در پارامترهای همودینامیک در جراحیهای مغز و اعصاب مطرح است که این تغییرات بسته به نوع، مدت و پوزیشن جراحی متفاوت می باشد، انجام تحقیقات تجربی برای تعیین تاثیر هر یک از عوامل فوق بر تغییر در پارامترهای همودینامیک توصیه می شود.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 1637

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 258 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    43-50
Measures: 
  • Citations: 

    2
  • Views: 

    944
  • Downloads: 

    467
Abstract: 

Background: Hepatitis B and C viruses are the most common causes of viral hepatitis, chronic hepatic disorders and cirrhosis. Since the true profile of hepatitis B and C was unknown in Kashan, the present study was performed on blood donors in Kashan during a 6-year period, 1996-2001.Materials and methods: For this descriptive study, all blood donors were included. Having their inclusion criteria fulfilled, they were asked for another 7cc venous blood before the cannula removed. HBSAg and HCVAb were determined using ELISA technique.Results: Of 43731 blood donors, 273 (0.6%) were HBSAg positive. The prevalence of hepatitis B was revealed to be 0.49-0.82. Meanwhile, 477 subjects (1.1%) were AntiHCV positive, thus the prevalence was 0.38-1.71.Conclusion: With respect to the prevalence of hepatitis C, this should be considered as a social health problem in Kashan. Fortunately, hepatitis B was controlled during the recent decade due to vaccination, observing health issues and improved monitoring of blood products

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 944

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 467 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 2 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 3
Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    729
  • Downloads: 

    445
Abstract: 

Background and objectives: It is essential to have a proper vessel route to do hemodialysis which is done by applying A-V fistula. In the current study complications and patency rate of side to side anastomosis with distal limb venous ligation have been evaluated during one year follow up. Methods and Materials: This study was undertaken on 62 randomized CRF patients whom received AVF by side to side anastomosis and patency rate of this technique were evaluated in six months and one year periods. Results: There was 12.9% complication which were mild and none of them needed reoperation. In this technique the patency rate was 93.56%. Conclusion: AVF by side to side anastomosis with distal venous limb ligation can have low complication and high patency rate. However, a longer time follow up and comparsions with other techniques are needed for more accurate conclusions.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 729

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 445 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    56-62
Measures: 
  • Citations: 

    0
  • Views: 

    983
  • Downloads: 

    283
Abstract: 

سابقه و هدف: آزبستوزیس بیماری حاصل از ترکیبات رشته ای شکل هیدروس سیلیکات است. رابطه مستقیم آزبستو با بدخیمی پرده جنب تایید شده و سل به عنوان یک عامل مستعدکننده در پیشرفت آزبستوز و نیز به عنوان یک عارضه در آزبستوز پیشرفته مطرح شده است. در این تحقیق رابطه بین تماس شغلی با محصولات آزبست و بروز سل ریوی، در کارخانه ایرانیت تهران در سال 1378 مورد بررسی قرار گرفت. مواد و روشها: دراین مطالعه یکسو کور که به صورت همگروهی تاریخی، صورت گرفت 202 کارگر تماس یافته با آزبست (گروه مورد) و 201 کارگر بدون سابقه تماس با آزبست (گروه شاهد) از نظر متغیرهای بالینی و پاراکلینیکی سل شامل اسمیر و کشت خلط، برونکوسکوپی، اسمیر و کشت مایع CXR, CBC, ESR, PPD, و BAL مورد مقایسه قرار گرفتند. یافته ها: گروههای مورد و شاهد به لحاظ سن، جنس، مدت اشتغال و مصرف سیگار مشابه یکدیگر بودند 7 نفر در گروه مورد و 1 نفر از گروه شاهد مبتلا به سل شناسایی شدند (p<0.04) ریسک شیوع تجمعی (CIR) 6.96 به دست آمد که نشان می دهد تماس با آزبست مستعدکننده بروز بیماری سل است. PPD مثبت بیش از 15mm در گروه مورد و شاهد به ترتیب %14.4 و %21.9 بود. مواجهه با آزبست از احتمال مثبت بودن تست توبرکولین می کاهد (p<0.05). نتیجه گیری و توصیه ها: مواجهه شغلی با آزبست احتمال خطر سل را می افزاید. با توجه به اینکه سل از نوع راکتیو بود. احتمالا کانونهای خفته سل در فرآیند آسیب ریوی آزبست فرصت فعال شدن می یابند. معاینات دوره ای کارگران صنایع آزبست در شناسایی بیماران در مراحل زودرس و درمان آنها مفید و لازم می باشد.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 983

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 283 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    63-68
Measures: 
  • Citations: 

    1
  • Views: 

    5363
  • Downloads: 

    202
Abstract: 

سابقه و هدف: با توجه به اهمیت خونریزی داخل مغزی در نوزادان که با مرگ و میر بالا و عوارض عصبی شدیدی همراه است و عدم اطلاع از شیوع و علل خونریزی داخل مغزی در نوزادان بستری شده در بخش نوزادان بیمارستانهای کاشان، این تحقیق در سالهای 1375-79 انجام گرفت.مواد و روشها: این مطالعه گذشته نگر بر روی 2755 نوزاد بستری شده انجام گرفت. پس از تایید خونریزی داخل مغزی، اطلاعات مورد نظر از قبیل سن حاملگی، جنس علایم بالینی، نوع زایمان، ریسک فاکتورهای مادری و نوع خونریزی، علت خونریزی از پرونده ها استخراج و در پرسشنامه مربوطه ثبت شد و مورد تجزیه و تحلیل قرار گرفت.یافته ها: در میان نوزادان بستری،62  مورد خونریزی داخل مغزی وجود داشت که 42 مورد در نوزادان نارس و 20 مورد در نوزادان ترم بوده است. مهمترین علت خونریزی در نوزادان نارس، آسفیکسی و در نوزادان ترم تروما بوده. شایعترین خونریزی در نوزادان نارس خونریزی داخل بطنی و در نوزادان ترم خونریزی ساب دورال به حساب می آید. ارتباط معنی دار بین خونریزی داخل مغزی و جنس نوزاد و نوع زایمان مشاهده نشد. شایعترین علامت بالینی در نوزادان مبتلا، کاهش رفلکس مورو بوده و مهمترین ریسک فاکتور مادری که خطر خونریزی داخل مغزی را افزایش داده بود پره اکلامپسی می باشد.نتیجه گیری و توصیه ها: با توجه به این که خونریزی داخل مغزی در نوزادان نارس 27 برابر نوزادان ترم بوده است و از طرف دیگر مهمترین علت به وجودآورنده آن نیز آسفیکسی بود باید تلاش بیشتری در جهت پیشگیری از زایمانهای پره ترم و بروز آسفیکسی انجام داد.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 202 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 1
Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    69-78
Measures: 
  • Citations: 

    3
  • Views: 

    1366
  • Downloads: 

    181
Abstract: 

سابقه و هدف: ارزیابی پایش رشد کودکان یکی از منابع مهم اطلاعاتی در تشخیص اختلال رشد و شروع سو تغذیه در کودکان است. هدف از این مطالعه تعیین روند رشد کودکان صفر تا 2 ساله تحت پوشش مراکز بهداشتی و درمانی روستایی شهرستان بابل در سال 1377 و مقایسه آن با منحنی استاندارد NCHS است. مواد و روش ها: تحقیق به روش existing data در سیستم پایش رشد کودکان تحت پوشش خانه های بهداشت شهرستان بابل انجام گرفته است. نمونه گیری به روش خوشه ای بود 429 کودک از میان متولدین 1373 تا 1375 با حداقل سن 2 سال از طریق دفتر ثبت موالید انتخاب شدند. صدکهای قد و وزن بر حسب سن و جنس محاسبه گردیده و با استاندارد NCHS مقایسه شده است. یافته ها: در یک ماهگی وزن %67.5 کودکان بین صدک پنجاهم تا نود و هفتم استاندارد بود، ولی با افزایش سن این رقم کاهش یافته است، به طوریکه در 6 ماهگی %45.2، در 12 ماهگی %42.6 و در 24 ماهگی %44.2 کودکان وزنشان بین صدک پنجاهم و نود و هفتم استاندارد بوده است. رشد دختران 5 تا 20 درصد کمتر از پسران است. با افزایش سن، کودکانی که وزن آنها بالای صدک پنجاهم استاندارد بود به پایین تر از صدک پنجاهم استاندارد افت کرد. نتایج نشان می دهد صدک پنجاهم وزن پسران تا 12 ماهگی و دختران تا 6 ماهگی بالاتر از صدک مشابه در NCHS است حال آنکه در سنین بعد ) تا 2 سالگی( زیر صدک پنجاهم استاندارد قرار می گیرد. همچنین اختلال در رشد قدی در سنین پایین تر 1-3) ماهگی( آغاز می شود بطوریکه در یک ماهگی صدک پنجاهم قد نزدیک به استاندارد است ولی از 3 ماهگی به بعد از صدک پنجاهم NCHS انحراف پیدا می کند. بطور کلی در صدکهای وزن و قد کودکان جامعه پژوهش در مقایسه با صدکهای NCHS اختلاف معنی داری مشاهده گردیده است (p<%5). نتیجه گیری و توصیه ها: قضاوت در مورد رشد شیرخواران ایرانی با استفاده از استانداردهای غیر ایرانی صحیح نمی باشد. بنابراین تهیه منحنی های رشد کشوری در ایران ضروری به نظر می رسد.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 181 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 3 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 2
Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    2009
  • Downloads: 

    446
Abstract: 

Background: The traditional classification of dermatologic diseases is based on etiology and clinical appearance, however, regional approach could be an appropriate alternatrive in clinical or research affairs. The present study was conducted in a dermatologic clinic in Razi hospital, Tehran to determine the frequency of cutaneous lesions of groin area and proposed the importance of a regional approach. Materials and methods: This cross sectional study was performed on 3401 patients referring consecutively. Diagnosis was made by clinical and paraclinical studies, if necessary biopsy was also taken. Meanwhile, sex, age and body mass index were all recorded. Results: Of 3401 patients, 3.9% had cutaneous lesions of groin area. Dermatophytosis, erythrasma, and seborrheic dermatitis were reported in 17.2, 14.9, and 14.9% of individuals. Lesions had shown significant differences according to the sex, and type of lesions. Conclusion: Cutaneous lesions of groin area are relatively common. Further regional approach studies are strongly recommended

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 2009

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 446 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    1381
  • Volume: 

    6
  • Issue: 

    3 (پی در پی 23)
  • Pages: 

    84-88
Measures: 
  • Citations: 

    3
  • Views: 

    3684
  • Downloads: 

    288
Abstract: 

سابقه و هدف: ازدواج فامیلی یکی از مهمترین عوامل معلولیت و بروز ناهنجاریها در نوزادان و کودکان می باشد بطوری که سالیانه هزاران نوزاد و کودک معصوم قربانی این ازدواج ها می شوند. جهت تعیین شیوع آنومالی های مادرزادی در ازدواج های فامیلی، این مطالعه در زایشگاه شبیه خوانی کاشان در سال 79-80 صورت گرفت.مواد و روش ها: در این پژوهش توصیفی، کل متولدین زایشگاه شبیه خوانی مشخص شدند و خصوصیات مربوط به جنس، سن حاملگی، نوع زایمان، کنترل حاملگی، مصرف دارو حین حاملگی، وجود بیماری خاص در مادر، نوع آنومالی (در صورت وجود)، سابقه مرگ یا آنومالی در فرزندان قبلی (در صورت وجود) و نوع آنومالی موجود در 24 ساعت اول تولد، مشخص و در صورت نیاز از سایر اقدامات تشخیصی، پاراکلینیکی و مشاوره نیز کمک گرفته می شد.یافته ها: در این تحقیق از مجموع کل 3529 نوزاد متولد شده در طول یک سال، %21.8 حاصل ازدواج فامیلی و %78.2 حاصل ازدواج عیرفامیلی بودند. 109 نوزاد (%3.1) دارای آنومالی بودند که از این میزان %7.03 در موارد فامیلی و %1.99 در موارد غیرفامیلی بودند 3.5) برابر(. از کل آنومالیهای موجود در ازدواج های فامیلی، %72.3 در ازدواج های فامیلی نزدیک و %27.7 در ازدواج های فامیلی دور بودند 2.6) برابر(.نتیجه گیری و توصیه ها: درصد ازدواج فامیلی در مطالعه انجام شده زیاد و میزان آنومالیها نیز در نوزادان حاصل از این نوع ازدواج ها بالاتر می باشد و در مواردی که ازدواج های فامیلی نزدیک روی داده است، آنومالی ها افزایش چشمگیرتری خواهد داشت. در این گونه ازدواج ها بیشتر آنومالیها از نوع ماژور خواهند بود.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 3684

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 288 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 3 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    2215
  • Downloads: 

    548
Keywords: 
Abstract: 

Background: Buxus hyrcana is species of Buxus genus. Buxus specien are known an The are of sterois alkaloids with biologic activity. They are widely Ysed in Traditicnal Medicine to Treat rhematism gout, skin diseases and Malaria nesistant to common therapies . therapies. The present study was carries out to extract steroid alkaloids from Buxus hyrcana gathered in uoshahr, Iran, and assessed its phytochemical chara cteristics.: Materials and Methods: For This exploratory study, The plant was dried regardless of exte heat or light. Then was powdered and ulraclecl using metharel. Turllur experiments enealed thal the produst contained alkaloids, and flavonoids. To txtract alkaloids , The product was exposed to Hcl s so thal ets PH reached 2. then chlorofcrn was osed to divide The chlovofornic phase contained non - alkaloids, wheras the olter phase contained and ets PH was reached Q By means of arncniurn , Finally chloroform wan wed for extraction During The Column chranatography of the chloro formic phase, an unpurified material was esolated that finally purified by thin loyer chromatography Results: The purified material had The following characteristics: UV absorption, Melting point of 170-173° C . molecular formula of And molecular mass of 385 Meanuhile, The presence of ketonic, alcoholic and amin groups as cyclopropanic cyclen wene all Cenfirmed.

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Issue Info: 
  • Year: 

    2003
  • Volume: 

    6
  • Issue: 

    23
  • Pages: 

    0-0
Measures: 
  • Citations: 

    0
  • Views: 

    32941
  • Downloads: 

    888
Abstract: 

Anaplastic cervical cancer in a virgin girl without any known risk factor, is rare. With respect to its rarity, severity and prognosis, we introduce a case referred to Shohada hospital in Tehran, in 1378. The case, a 31 years old virgin girl with acute urinary retention, anemia, fever and abnormal uterine bleeding was admitted. Many times, she expelled vaginally some tissues with pathologic report of highly malignant neoplasm of unknown cellular origin. Regarding clinical and paraclinical data, the patient underwent radical hysterectomy (Wertheim) and pelvic lymph node dissection. Pathologic report was highly malignant anaplastic neoplasm with massive lymphatic invasion to cervix. The operation followed by chemotherapy and radiotherapy. Five months later, the patient managed by chemoradiation, because of recurrence of tumor in para-aortic lymph nodes. Finally nine months following the first diagnosis, she expired from uremia. In conclusion, supposing unknown risk factors for cancer of cervix, probability of this cancer in virgins should be considered. Early detection of cervical cancer in this group who are apparently without any known risk factors, is of utmost importance.

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 888 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 1