SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES
Year:2000 | Volume:5 | Issue:1 (SERIAL NUMBER 17)|Papers Count:12

INTRODUCTION: Irritable bowel syndrome (IBS) is the most common disorder of gasterointestinal tract. The prevalence of IBS is between 14% to 22%. This study was aimed to demonstrate the relationship between post nasal discharge (PND) and IBS. MATERIALS & METHODS: This was a case- control study. The case group including 67 patients with IBS and no history of psychologic or chronic disorders, refered to a clinic of internal diseases, were compared with 75 patients without IBS selected by paired matching method. RESULTS: Of patients with IBS, 59.7% (40 cases) were male and 40.3% (27 cases) were female. Mean age of the patients was 27.9 years (SD= 8.73). In 41.8% of the patients (28 cases) evidences of sinusitis were found in radiography of paranasal sinuses. Sinusitis had a signtificant association with IBS (P=0.01, OR= 4.27, CI= 1.19- 16.74, x2= 5.37). PND was also significantly associate with IBS (P= 0.001, CI= 2.99- 13.99, x2=18.69). CONCLUSIONS: Our Study confirmed the realationship between upper respiratory tract infections, particulaly sinusitis, and IBS. This may suggest that IBS is a systemic disorder involving multiple organ systems.

INTRODUCTION: DMFT index (decayed, missing and filled teeth) and percent of caries-free children are two important criteriae in evaluation of children health in community. The purpose of this study was to determine DMFT index and related factors in 12- year- old school children in Sanandaj city. METERIALS & METHODS: This study was a cross-sectional research.The subjects were 430 students who have 12- year- old age (224 boys and 215 girls). They were selected by stratified random sampling method. The data collection methods were interview and examination of teeth. RESULTS: The results showed that mean DMFT was 2.6. in all students.DMFT in girls was 2.52 and in boys was 2.67 which were not significantly different (P=0.392). Fifteen percent of students had no caries in their permanent teeth. Sixty two percent of students didn`t brush their teeth at least once a day. There was significant relationship between sex and tooth brushing so that the girls brushed more than boys. There was also significant relationship between monthly income and degree of offsprings with dental caries (P=0.026, P=0.04 respectively).There was no significant association between sex, number of family members, parent`s level of education and parent`s employment with dental caries. CONCLUSIONS: The result of this study shows that screening programs can provide important information about direct health education and control of other health problems in school health programs.

INTRODUCTION: Colorectal cancer is a relatively common cancer of gasterointestinal tract. It has a world wide distribution with different prevalence among countries. This research was aimed to demonstrate the periodic prevalence of cancers of colon and rectum in Kurdistan province during 1995-1999. MATERIALS & METHODS: The subjects were total number of patients with colorectal cancer who diagnosed during 1995-1999 (100 cases).Data was collected from patient`s files and archieves of pathalogy centers in Sanandaj. RESULTS: In our study the relative frequency of colon and rectum cancers were 62% and 38%, respectively. Ninety percent of cancers were adenocarcinoma while 7% were lymphoma and 3% were carcinoid tumor. Sixty one percent of patients were male and 39% were female. The prevalence of colorectal cancer in general population was 7/100000 during 1995-1999. The most common age of colorectal cancer was above 60 years old. The mean age of the patients was 50 years old. The range of patient`s age was between 4 to 93 years. Most patients were diagnosed in 1999 (30 cases). CONCLUSIONS: Colorectal cancer had relatively high incidence rate in Kurdistan province in our study. We recommend further evaluation to detect risk factors for colorectal canecrs here.

INTODUCTION: The aim of this study was evaluation of health service serving in Kurdistan`s health houses in 1998. MATERIALS & METHODS: Data was collected from 166 health houses throughout the province by (multistage) random sampling. We used a questionnary including 165 questions for evaluation of health systems and multiple practices in health houses. Computerized analysis of data was performed by measuring 2 and variance analysis. RESULTS: Forty seven percent of female health workers and 49% of male health workers were not native. More than 50% of both male and female health workers were not resident in health house of main village. Eeighteen percent of them were resident in the city. The coverage of vaccination and caring of pregnant women were 96% and 91.5%, respectively. They were significantly different in health systems throughout the province (P=0.013). Family planning coverage was 73% and it was significantly different among health systems (P=0.003).Coverage of infant`s care was 86% and there was no significant difference among health systems (P=0.621). CONCLUSIONS: Coverage of vaccination and caring pregnant women were acceptable while there was significant problems regarding health house building, residency of health workers, using native health works, providing essential drugs, health supports, official and pecuniary supports, continuous program for travelling physician and health team and environmental health (microbiological analysis of water, hygienic toilettes, water chlorinating) that warrant further attentions and supervisions by responsible managers.

INTRODUCTION: This study was aimed to evaluate changes in number and distribution of mast cells in seminal vesicles of rat during acute phase of spinal cord injury (SCI). MATERIALS & METHODS: This research was a randomized clinical trial. Forty three 2- month-old rats of sprague race were selected and divided to the control and case groups. In the case group spinal cord disscection at the level of T9 was performed following local anesthesia and laminectomy. In the cotrol group, only laminectomy of the T9 was performed but the cord remained intact. In both groups biopsy from seminal vesicls was perfomed in the first, second and third weeks after surgery. Serial sections of speciments were stained with Toluidine-blue. Then mast cells in the connective and mucusal tissues were counted. The results were analysed by mann whitney U test. RESULTS: The number of mast cells in the case group was increased as compared with control group both in the first (11.63± 0.59 versus 8.014± 0.22) and second 8.14 ±0.85 versus 70.7 ±7.84) weeks (P<0.001). CONCLUSIONS: Increased number of mast cells, particularly mucusal mast cells, is due to epithelial damage during actue phase of SCI. This may be a cause of increase in antibody titer in the semen that may have a roll in infertility of the patients with SCI.

INTRODUCTION: This study was conducted to demonstrate the demographic characteristics, clinical and laboratory findings of the patients with primary small intestine lymphoma in educational hospitals in Isfahan. MATERIALS & METHODS: We studied the files of patients with primary small intestine lymphoma admitted in Al-zahra, Amin, Feys and Ayat- Allah Kashani hospitals between 1989 to 1994 (5 years). Data including age, sex, blood group, chief complain, physical signs, laboratory and radiological findings, medical and surgical therapies and pathology of the tumors were collected from the patient`s files. RESULTS: The subjects were 30 patients with primary intestinal lymphoma. Half of the patients (15 cases) had below 5-year-old. Twenty five patients (83.3%) were male and 5 patients (16.7%) were female. Abdominal pain was the most common chief complain (22 patients). In 43% of patients (13cases) the lymphoma was diagnosed by paraclinical methods. The most common laboratory finding was anemia (83.3%). In all cases abnormal findings were seen in the small bowel series. The total time of admission was 6 to 10 days in 46.7% of the patients. Thirty percent of the patients was admitted for 11 to 15 days. All cases were non Hodgkin`s lymphoma (NHL) which 53.3% were high grade. The most common subtype in the high grade lymphoma was small non cleaved (46.7%). CONCLUSINOS: Small intestinal lymphoma has no characteristic finding. So, every patients with abdominal pain, abdominal mass or weight loss should be evaluated regarding the small intestinal lymphoma

INTRODUCTION: Headache is a frequent complain in premenstrual syndrome (PMS).Menstrual headache is the headache that occure before or during menstruation. This often appeare as migraine or tension type headache and usually disappear after the first day of vaginal bleeding. MATERIALS & METHODS: This was a cross-sectional study to demonstrate the frequency of migraine (menstrual and nonmenstrual) and it`s related factors in 700 female students (between 18 to 25 years of age) with premenstrual syndrome. The data was collected by questionary. RESULTS: Of 700 female students with premenstrual syndrome, 115 persons (16.4%) had menstrual headache and 144 presons (20.5%) had headache independent to menstruation. Of these 259 studens with headache, 60 persons(23.1%) had migraine headache.Of these persons with migrain, 35 persons (13.5%) had menstural migraine and 25 persons (9.6%) had migraine independent to mensturation. The overall prevalence of menstrual migraine was 5%. Our study confirmed the significant association between migraine and regularity of menses, family history of migraine, number of offsprings and menstrual headache (P<0.05). However, no significat association between migraine, marrying and family history of PMS was found. CONCLUSIONS:Menstrual migraine is a relatively common problem in female students.So, routine evaluation of students regarding menstrual migraine is recommended.

Teratoma is the most common ovarian and extragonadal germ cell tumor. Sacrococcygeal teratema is the most common teratoma in infancy. It has an incidence of 1 in 25000 to 40000 live births. A rare case of huge sacrococcygeal teratoma is presented here. He was a newborn with a very largy mass in his sacrum who born by cesarean section. The mass had a cystic and vascular appearance. It`s size was 20 ×40 ×60cm. The weight of the newborn was 9kg (including the mass). He had no other abnormal finding upon clinical examination. He was normal urination and defecation. Surgical resection of the tumor was performed in 4 th day after birth. The weigh of the mass was 6 kilogram. Diagnosis of mature teratoma was histologically confirmed. Benign teratoma usually cause only functional disorders such as intestinal or urinary obstraction. In this case, however, there was also no functional disorder despite huge mass of the tumor

Apoptosis is a common form of cell death. The biological significance of apoptosis in pathogenesis of cancer , fetal development and normal immune response has been recognized widely since two last decades. Apoptosis, like as proliferation, is a major factor in function of most cells including bone cells.Bone is a calcified tissue with a few number of cells. So, it is defficult to study apoptosis of bone cells.There is several methods for detection of apoptosis that include: gel electrophoresis, electron microscopy, light microscopy, nick-end labelling of DNA , fluoresence techniques, and detection of phosphatidyl serine.These techniques also demonstrate the affected components in the cell during apoptosis.New methods lead to a better understanding of the mechanism of action of drugs currently used to treat patients with bone diseases, and possibly production of new drugs designed to maintain or increase bone mass by either promoting or preventing apoptosis of bone cells.