In order to reduce the country’s dependence on oil revenues and develop new sources of foreign exchange earnings, using its great potential of natural gas resources and preserve and broaden its geo-economic role in the region and the world, the Islamic Republic of Iran should implement a high-profit, low-risk, and reliable trading strategy for macro scale selling of its natural gas. The main question of this paper is that, among the five major trading markets, namely the Persian Gulf, Indian Subcontinent, East Asia, China, and Europe, which one has the above said strategic features and criteria.