The aim of this research was to investigate the effect of transformational leadership on the tendency to change with the mediating role of de-learning in Nirpars company. This research is applied in terms of purpose and descriptive and correlational in terms of nature, which is a cross-sectional survey method. The method of work in this research is field and the type is case study. The statistical population of this research consists of all managers, heads, experts and employees of Company located in Tehran to 281 people. In order to collect the information in two parts of transformational leadership and the tendency to change the questionnaire have been prepared by the researcher, and in the de-learning section, a standard questionnaire (Khodaei et al., 2014) has been used. The statistical sample of the research is a simple random method. After confirming the content validity with the opinion of experts and professors, the reliability of the questionnaires through Cronbach's alpha for the "Transformational Leadership", "Tendency to change" and "unlearning" questionnaires were 95. 8%, respectively. 72. 9% and 70. 8% and Cronbach's alpha coefficient for all questionnaires were 93. 3%. To hypotheses examination, "Correlation coefficient", "Multiple regression model" and "Structural equation modeling" tests were used by using of SPSS and LISREL softwires. Overall investigation showed that there is a positive and significant relationship between dimensions of transformational leadership with tendency to change, between dimensions of transformational leadership with unlearning and between the dimensions of unlearning with tendency to change.