Background: Spouse abuse consists of: aggression, beating and slapping, affront, mental- social- economic- sexual abuse and etc. The side for wives effects range from physical, mental and social harms to death. There are few studies on this subject in Iran; therefore we designed a survey to study its situation in Isfahan city of Iran. Methods: In this Cross Sectional study with Cluster Random Sampling, we selected 4 serial houses from 50 blocks of 495 blocks according to map of Isfahan city and 386 married women were interviewed using standard questionnaire.Results: The mean age of these women was 35.7 (15-78) years and the mean age of marriage was 19.3 (9-44) years, 2.4% of them were foreigners, 1.8% Christian and others Muslim, 7.5% of them were illiterate. Prevalence of smoking-alcohol and drug abuse was 0.5% in them and 33.7%-7.8%-5.7%.Respectively in their husbands prevalence of spouse abuse from marriage time was 36.8% and incidence rate was 29.3% in recent year. The most common time of spouse abuse was in the night. The most common types of it were: disregarding wives' feelings 45%, aggression 43%, unconsented intercourse 31%, forced intercourse 18%, insecurity at home 15.8%. Threat to: Discontinue relations with other family members 38%, Affront 32%, Beating 24%, quitting 18%, Divorce 15%, Death 7%, knifing 6%, Gunning 2%. Making problems such as: financial 10%, House- Clothing- Food supplies 14%- 14%- 8%. History of: Slapping 32%, humiliation 29%, Beating 27%, Knifing 3.4%.Conclusion: Given the high prevalence and incidence rate of spouse abuse, we suggest that an analytical study to identify the risk factors of spouse abuse in our community be carried out and public enforce on mutual rights and duties of wives and husbands planned and performed.