To provide guides for exploration of porphyry copper mineralization at a district scale, the spatial association between known copper deposits and geologic features in south central Iranian volcanic belt was examined, with the use of Landsat TM images. After several corrections, geological intrusive bodies and intrusive margins, fault-fractures and alteration haloes were extacted using 741 and 754 bands, PCA, DEM and filtering techniques. The spatial associations between the porphyry copper deposits and fault-fractures, batholithic pluton margins and porphyry plutons are quantified using weights of evidence modeling. The porphyry copper occurrences are associated spatially with fault-fractures, intrusive margins and contacts of porphyry plutons within distances of 1 and 2.5km, respectively. In addition, the porphyry type mineralizations are associated spatially with strike-slip fault fracture and contacts of intrusive bodies within a distance of 1 and 1.5km, respectively. Based on these observations, local strike-slip faults related to regional strike-slip faults systems are the most important foci for emplacement of copper-bearing porphyritic intrusions in the study area. Then using fuzzy logic method, and based on the results of weights of evidence modeling, the quantified favourable potential regions and study area, according to porphyry copper potential model, are divided to four parts namely; favourable, moderate, weak and unfavourable.