Hormozgan Medical Journal
Year:2002 | Volume:6 | Issue:3|Papers Count:11

This prospective study was conducted to find out The accuracy of Pathergy test, which is the hyperactivity of skin to needle trauma, in patients with behcets disease, and to compare the results with current universal method, using disposable sharp needles in patients with (BD) in South West of Iran.The study was done during April 1996 - August 1998 in Behcets Disease Research clinic in Shiraz university of Medical Sciences.The pathergy phenomenon was tested simultaneously on the skin of forearm on 104 (71 female and 33 male) BD patients with active disease and on 100 healthy persons as control group. two methods for pathergy test were used: 1- the old method, using the blunted needles that were non-disposable, sterilized 21 gauge (G) needles and 2- the new current standard method with sharp-disposable needles, in three different gauges including: 21G, 23G plus intradermal injection of 0.1cc normal saline (N/S) and skin scratches by 25G needles. The skin reactions were checked 24-48 hours later by the same physician for possible developing erythema of more than 2mm in diameter, papules or pustules at the sites of needle insertion (called positive pathergy test). At the end of 17 months, the data were analyzed to compare the sensitivity and specificity of the both tested pathergy phenomenon by blunt and sharp needles.By using the blunt needles, positive pathergy test was seen in 85 out of 104 BD patients and in 3 out of 100 of healthy control group, (sensitivity of 80.7% and specificity of 97%).The pathergy test with more traumatic method, that is using intradermal injection of 0.1 cc N/S with 23G sharp needle insertion, resulted 69 out of 104 patients with positive test and 3 out of 100 in healthy control persons (sensitivity of 66% and specificity of 97 %).In this study we observed that using non-disposable, sterile blunt needle in performing the pathergy test in BD patients (old method) increases the sensitivity of pathergy test to 80.7% in comparison to current standard method in which disposable-sharp needle is being used.

Labor has two phases, latent phase and active phase. Active phase begins from 3- 4cm dilatation of cervix and finishes at dilatation of 10cm. The mean duration of active phase is 4.9 hours in primpara and 3.2 hours in multipara.Atropine is an anticholinergic drug and is used empirically in many obstetrical centers for shortening of active phase, but there is no report of studies on the effect of atropine on the duration of active phase in texts.This empirical double blind clinical trial was conducted to determine the effect of atropine on the duration of active phase.Simple sampling was used to select subjects. Subjects were 459 pregnant women between 18-35 years in Shariati hospital who had no risk factor in pregnancy or contraindication for normal vaginal delivery and all had 3-4cm cervical dilatation. The mean duration of active phase in 125 priniparous women.Out of 249 primiparous women who received atropine was 139.2±65.5 minutes and in 124 patients who received placebo were 118.4±48.2 minutes. The mean duration of active phase in 97 multiparous women out of 210 multiparous women who received atropine was 72.1±19.3 minutes and in 113 women who received placebo it was 65.1±51.1 minutes. The results of reveals that atropine seems not to be effective in shortening of active phase in multiparous and nuliparous women.

Coronary Artery Disease (CAD) is one of the most common and fatal diseases in the world. The primary management of CAD is medical, but Coronary Artery Bypass Graft (CABG) is a reliable method of treatment for these patients. Evaluation of the exercise test and echocardiographic results before and after CABG was the main purpose of this study.This clinical trial was performed on 40 (28 male and 12 female) patients who were candidate for CABG. All patients had exercise test and echocardiography before and 3 to 6 months after their surgery. Chi squre and paired t-tests were used for data analysis.The average age of patients was 59.2 years. The mean Left Ventricular Ejection Fraction (LVEF) before and after CABG was 50.2% and 50%, respectively, with no significant change. Exercise test was positive in 93.3% of patients before and 36.7% of them after CABG. This difference was statistically significant (p=0.001). Mean time of exercise test was 6.7 minutes and 8.3 minutes before and after CABG, respectively (p=0.01). Prevalence of dyspnea, angina pectoris and positive exercise test before surgery were 63.3%, 83.3% and 93.3% which declined to 16.7% and 36/7 % respectively. These changes were also statistically significant.Our study showed that CABG was effective for exercise test tolerance improvement, reduction of dyspnea and angina pectoris but didn't have any role in LVEF improvement.

Bacterial, viral, parasitic and fungous infections in human and animals are related to abortion and mycoplasmas are the more prevalent causes of it.Studies about genital mycoplasmain abortion have been conducted so far. The present study was designed to investigate the incidence of these micro organisms in the endocervix of women seeking abortion in comparison with that of the control group.A sample of 125 women with abortion and 250 women as control group was tested by the filtration technique in culture media. The case and control groups were matched based on age, education and job.Results showed that isolated bacteria in aborted cases were higher than control group. 14.4% of the cases were infected with mycoplasma hominis and 31.2% with ureaplasma urealyticum: The statistical analysis showed significant differences between case and control groups, both in mycoplasma hominis and in ureaplasma uralyticum (p<0.05).In conclusion, according to the statistical analysis, there is a significant relationship between these bacteria and abortion and presence of these bacteria's in endocervix should be noted and treated.

There is relatively a lack of information about effect of atenolol on thyroid hormones. There are many studies and reports in the literature about properties of propranolol that increases TT4 (Total T4) and decreases TT3 (Total T3). This study was designed to asses' effect of atenolol on plasma TT4 and TT3 in 15 subclinical hyperthyroid patients. Plasma concentration of TT4, TT3 and atenolol were determined in 3 different times after starting the use of atenolol (100 mg/d). The plasma concerntration of TT4, TT3 and atenolol on first, third and seventh days after starting of drug administration was determined. Statistical evaluation of the measured concentration showed that TT4 in third and seventh day compared to the base TT4 had increased significantly (P=0.05, P=0.001). The same measurement was done with TT3 but the results were not statistically significant. In this study it was revealed that there is no correlation between the atonolol plasma concentration and TT4 or TT3 concentration.

This research was performed in order to compare oxygen consumption rate along the sewerage.To assess the existing conditions, Sahebgharnie main pipeline with the length of 300m and diameter of 300mm was investigated and dissolved oxygen concentration was measured in ten points of its length.While concentration of dissolved oxygen in the first manhole was 2.73mg/l, its concentration at the last segment decreases to 1.8mg/l in the manhole. Oxygen consumption rate along the sewerage was calculated as much as 8.99mg/l.h.The h/D (sewerage slope) ratio for the first and last spot of the sewerage was measured 4.5% and 29.7% respectively, expressing the fact that dissolved oxygen will decrease if h/D ratio increases. The amount of BOD5 was also measured 195 mg and temperature was 20.3.Using this calculation for other systems, it will be possible to prevent biological corrosion sewers.

Tuberculosis is an important infections disease in Iran and due to its cosmopolitan recurrence; it has been taken into serious consideration. This disease was the world's leading cause of death among other causes, accounting for one fatality in every seven cases.This study was conducted to determine the incidence rate of all forms of tuberculosis and sputum positive pulmonary TB in Barn during 1995-2000.Mycobacterium tuberculosis was isolated in 401 patients out of 2486 who referred to physicians and health centers. 56.6% of patients were female and 46.4% were males aged between 2 to 90 years old with mean age of 45.6 years. 53.4 % of patients lived in rural areas and urban areas 5.7 % of cases were in prison. All patients had radiological finding of pulmonary TB.77% of patients had a positive smear. Regarding the location 80.7% of cases had pulmonary tuberculosis and 19.2% had infection in the other organs. In 1995, recorded cases of TB were in the highest peak of incidence.

Methotraxate (MTX) is an immunosuppressive drug which has become popular as a therapeutic choice for psoriatic arthritis and rheumatoid arthritis. Pneumonitis is emerging as one of the most unpredictable and potentially serious adverse effects of treatment with MTX. Its prevalence in rheumatoid arthritis has been estimated from several retrospective and prospective studies to range from 0.3 % to 18%. On the other hand MTX induced Pneumonitis seems to be very rare in psoriatic arthritis.Here in we introduce a 63 years old woman with psoriatic arthritis, who came to us because of dry cough from 18 months ago. She was treated with MTX for 18 years and her disease was in remission. Chest high resolution CT-Scan (HRCT) was done and diagnosis of MTX-induced Pneumonitis was made, based on the Carson and Kremer diagnostic criteria. Discontinuation of the drug led to improvement after 3 months.