Introduction: Common carotid artery intima-media thickness (CCA-IMT) correlates with cardiovascular mortality in patients under hemodialysis. In this investigation, we evaluated relationship between CCA IMT with dependent and independent cardiovascular risk factors in chronic hemodialysis patients.Methods: In this cross-sectional study, 51 chronic hemodialysis patients, (31 males and 20 females) were enrolled. left and right CCA-IMT were measured using high resolution B-mode ultra sonography and maximum measure was considered. Based on ultra sonographic findings, patients were divided into two groups, one with carotid intima thickness of ³0.8 mm and another group with carotid intima thickness of <0.8mm. Data was analyzed, using Minitab software.Results: Mean age of these with carotid intima thickness ³0.8mm was significantly higher than these with carotid intima thickness <0.80mm (P<0.05), (60.7±8.4 vs 41.3±18.7). Although, there were differences in hemodialysis duration, systolic and diastolic blood pressure, blood cholesterol and triglyceride LDL, diabetes and smoking history of these two groups, but the differences were not significant.Conclusion: This study indicates that there is no significant correlation between CCA-IMT and cardiovascular risk factors in chronic hemodialysis patients.