Armaghane Danesh
Year:2016 | Volume:21 | Issue:9 (116)|Papers Count:9

Background and aim: The use of exercise along with herbal supplements is one method proposed for controlling obesity and its complications. The aim of this study was to investigate the effect of 8 weeks aerobic training and use of hydro-alcoholic extract of nettle on levels apelin and hs-CRP plasma in overweight and obese women.Methods: The present quasi-experimental study was conducted with blind randomized clinical trial.46 overweight and obese women (body mass index greater than 25 kilograms per square millimeter two, aged 25-45 years) were selected purposefully and randomly divided into four groups of: aerobic training+hydro alcoholic extract of nettle, aerobic exercise+placebo extract of nettle and placebo. The intervention group and placebo received 8 mg of hydro alcoholic extract of nettle 8 ml of water-soluble daily for 8 weeks respectively. Aerobic exercise ergometer for 8 weeks, 3 sessions of 16 to 30 minutes with the intensity of 60-75% heart rate was reserved. In two pre and post-test after 14 hours of fasting at the same conditions, blood samples were collected. The ELISA method was use to assess levels of plasma apelin and hs-CRP d. Data obtained were analyzed using the Kolmogorov-Smirnov test, ANOVA, t-test and LSD test.Results: The results showed that the levels of hs-CRP were significantly different in comparison among the groups as well as in groups of aerobic exercise+hydro alcoholic extract of nettle, nettle and hydro-alcholic aerobic exercise+placebo significant reduction was observed (p>0.05).Conclusion: It seems that consumption of Nettle extract along with aerobic exercise through Weight loss, body fat percentage and BMI, play an effective role in control of obesity and reducing of inflammatory Apelin markers and hs-CRP in obese women.

Background and aim: Gentamicin is an aminoglycosides antibiotic which is used to treat several types of bacterial infections. The aim of this study was to evaluate the effects ofNigella sativa extract on renal toxicity in rats induced by gentamicin.Methods: In the present experimental study, 42 Wistar male rats were divided into 6 groups of 7 includes: control (normal saline 2ml/kg, i.p), gentamicin (gentamicin80mg/kg/day, i.p), positive control (400mg/kg NSE, i.p) and treated groups 1, 2, 3 (gentamicin 80mg/kg/day+NSE 200, 400 and 800 mg/kg respectively, i.p). Nigella sativa extract was injected for 7 days after a ten days period of gentamicin injection.Results: Gentamicin caused necrosis and inflammation in the renal cortex and medullary tissues. Treatment withNigella sativa seed extract significantly decreased serum creatinine, BUN and serum LDH in treated groups compared with the group receiving gentamicin. The greatest impact was created in high dose (P=0.001).Conclusion: Nigella sativa seed extract reduces inflammation caused by receiving gentamicin in kidney tissue and a significant reduction in creatinine, urea nitrogen and lactic dehydrogenase enzyme in treated mice compared with the control group.

Background and aim: The prevalence of cardiovascular diseases have their roots in inflammation and systemic inflammation plays an important role in the development and progression of atherosclerosis. ICAM-1 is an indicator of inflammatory in the pathogenesis of atherosclerosis, which the effect of exercise and herbal remedies response are not well understood. The aim of the present study was to evaluate the high intensity aerobic interval training (HIIT) and flaxseed oil on ICAM-1 gene expression in heart tissue of male Wistar rats.Methods: Thirty Wistar rats were chosen and randomly divided into six groups of five including control, exercise, extracts dose of 10 mg/ kg, dose of 30 mg/kg of extract, extract exercise dose of 10 mg/kg and 30 mg extract mg/kg exercise groups. Group of exercise have done five sessions per week for 10 weeks, intense interval training consisted of running 90 to 95 percent VO2max intensity treadmill for rodents, at specified hours during the day. At the end of experiment the rats were sacrificed and heart tissue was prepared to measure gene expression of ICAM-1 and LFA-1.The data were analyzed by ANOVA statistical tests.Results: The data in the exercise group significantly reduced the expression of ICAM-1) p<0.039 and extract respectively. ITG also expressed in the exercise group (p<0.01) and extract decreased significantly. Data analysis showed that the expression of ICAM-1 has been reduced in training supplement groups.Conclusion: Compound exercises and flaxseed oil reduces the expression of ICAM-1 compared to control group, so it is likely that this method can be used as a way to prevent cardiovascular disease.

Background and aim: The risk of cardiovascular disease in women increases after menopause.The aim of this study was to investigate the effect of aerobic exercise at moderate intensity levels of cystatin C and some cardiovascular risk factors in inactive postmenopausal women.Methods: In this quasi-experimental study, 24 sedentary postmenopausal women (50-65 years) were randomly divided into two experimental groups (n=14) and control group (n=10) groups. The experimental groups performed an aerobic training with 65 to 75% of maximum heart rate, 3 days per week for 10 weeks. Body fat percentage and serum levels of cystatine C with high sensitivity, C-reactive protein, HDL, LDL, triglyceride, cholesterol and blood pressure were measured at baseline and after training. Data were analyzed using analysis of covariance test.Results: No significant difference was seen after performing aerobic training on serum levels of cystatin C (p=0.761), C-reactive protein with high sensitivity (p=0.378), triglyceride (p=0.48)), high-density lipoprotein (p=0.54), low-density lipoprotein cholesterol (p=0.86), cholesterol (p=0.67), percent body fat (p=0.57) between the two groups. There was no significant difference between control and experimental groups in the variable maximal oxygen uptake (p=0.035) and systolic blood pressure (p=0.04).Conclusion: It seems that short-term aerobic training have no effet on serum levels of cystatin c and some moderate-intensity cardiovascular risk factors like reactive protein C, total cholesterol, high density lipoproteins, lipoprotein help disabled density and blood pressure in in inactive postmenopausal women.

Background and aim: Adverse effects inner anger and interpersonal relationships will follow on from the other parent behavior management training and promoting and improving relations between parent-child.Methods: The present Experimental research used a pretest– posttest and a control group. The population consisted of male and female junior high school students in Tabriz who were enrolled in the 2012-2013 school year. Therefore, after screening by the teachers and the Nelson anger questionnaire, 30 children who, according to scores on the questionnaire were bullies, were classified randomly into two groups of 15 cases and controls were replaced and after completing the questionnaire anger Nilsson (2000) bullying by students, parents groups for 9 sessions (45 minutes each) were treated in a management training program, while the control group received no training. Parent Management Training participants after the end of the session, were reviewed and followed a month later. Data were analyzed by the SPSS version 18 statistical software using descriptive indicators and multivariate analysis.Results: The results indicated the effectiveness of Parent Management Training to Reduce Anger of the teen bullies (P<0.05), respectively. The results of the follow-up phase difference (P<0.05) between the test and control groups, respectively.Conclusion: The findings revealed that the behavioral management training had been effective in reducing anger bullying teenagers that might have been due to the effect of education on their daily relations.

Background and aim: Psychological consequences of addiction, such as major depression regardless of physical problems, economic, cultural and social is cause problems for both families and society. The aim of this study was to evaluate the effectiveness of group cognitive hypnotherapy on major depression in residential and semi-residential addiction recovery centers in the city of Yasuj.Methods: The present quasi-experimental study was conducted using a pre-test, post-test and control group. The population included all patients drug dependent as residential and semiresidential referred to Yasuj addiction recovery centers.40 patients were selected by convenience sampling and randomly assigned to experimental and control groups. The instrument used in this study included Beck Depression Inventory which depressed patients diagnosed and according to clinical interview they entered the study. Group cognitive Hypnotherapy intervention model was carried out on the experimental group for 8 sessions for one hour once a week, but there was no intervention on control group. After the intervention both experimental and control groups were assessed. Collected data was analyzed using covariance analysis.Results: The results revealed that the cognitive hypnotherapy treatment of group, leading to depression reduced significantly in the experimental group compared control group significantly (p< 0.001). The mean pre-test score of major depression in the experimental group and in control group was 39.5±10.54 and 61.4±20.52 respectively. Where as the mean and standard deviation of major depression and post-test scores in the experimental group 55.2±05.25 and in the control group was 50.3±55.51.Conclusion: Cognitive hypnotherapy can be used as adjunctive therapy in reducing major depression or used in addiction recovery centers.

Background and aim: Acute phase proteins are proteins built by factors such as inflammation, necrosis, bacterial infection, virus and malignancies and its value will changes in plasma and serum. UTI is one of the probable infections that changes this protein.The main purpose of this study was to determine the relationship between serum C- reactive protein and causative factors in patients with urinary tract infection was in 1393.Methods: In the present cross-sectional study, 2400 patients with suspected urinary tract infection were referred to medical clinics during five months urine culture were performed. ELISA and turbidity test were used to measure the amount of blood C- reactive protein. The urinary tract infection in patients with more than 105 colonies was considered as a positive culture, and then phenotypic test infection was performed by API kit. In addition; to confirming the results obtained DNA Sequencing experiments were conducted on genes Sr RNA 16. The data was analyzed using descriptive statistics and Chi-square tests.Results: Among the total of 2400 patients with suspected urinary tract infection, 100 patients had positive culture with 69%E.coli, 10% klebsiella, 6% enterococcus, 5% Enterobacter 2% and 3% were the other bacteria respectively. The results indicated that the level of CRP in the UTI patients increased to 56.8%. In addition, no association was found between blood levels of C- reactive protein and the type of the bacterial agents.Conclusion: The level of C- reactive protein blood was inceased in urinary tract infections increased, but this increase is not related to the type of bacteria.

Background and aim: Polycystic ovary syndrome is a common endocrine disorder that is associated with lipid disorders and obesity with an increased risk of cardiovascular disease. The aim of this study was to determine the association between lipid profile and fasting blood sugar levels and insulin resistance among women with polycystic ovary syndrome.Methods: The present case-control study was conducted on 153 women with PCOS and 449 healthy women as controls. Data was extracted from data center of Diabetes Research Center of Ahvaz University of Medical Sciences including women from 4 cities of Khuzestan province (Ahwaz, Behbahan, Abadan, and Khorramshahr). Serum lipids, fasting blood sugar, and serum insulin levels along with Body Mass Index (BMI), Homeostatic Model Assessment Insulin Resistance (HOMA IR), Lipid Accumulation Product (LAP), and Body Adiposity Index in two groups were analyzed by independent t-tests, chi-square and Fisher exact test.Results: The frequency of low HDL and high total cholesterol was higher in women with PCOS than control group (p=0.032, and p=0.001, respectively). No significant difference was seen between No two groups in the mean levels of total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, fasting blood sugar, HOMA IR, LAP, and PA (p>0.05). In women with BMI<25 and BMI between 25 and 30, the mean level of total cholesterol was higher in PCOS group than control group, whereas there was no significant difference in women with BMI>30. In women with BMI>30, the mean triglyceride and glucose levels was higher in PCOS group than control group (p=0.029, and p=0.010).Conclusion: In the present study, in obese women, triglyceride and fasting glucose levels were higher in patients with polycystic ovary syndrome than healthy women. In non-obese women, however, the total cholesterol level was higher in patients with polycystic ovary syndrome than healthy women.