THE EFFECT OF HIGH INTENSITY AEROBIC INTERVAL TRAINING (HIIT) AND FLAXSEED OIL ON ICAM-1 GENE EXPRESSION IN HEART TISSUE OF MALE WISTAR RATS

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KHADEMI Y.; AZARBAYEJANI M.A.; HOSSINI A.

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Journal: Armaghane Danesh Year:2016 | Volume:21 | Issue:9 (116) Page(s): 873-886

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Title

THE EFFECT OF HIGH INTENSITY AEROBIC INTERVAL TRAINING (HIIT) AND FLAXSEED OIL ON ICAM-1 GENE EXPRESSION IN HEART TISSUE OF MALE WISTAR RATS

Author(s)

KHADEMI Y. | AZARBAYEJANI M.A. | HOSSINI A. | Issue Writer Certificate

Keywords

CARDIOVASCULAR DISEASEQ1

INFLAMMATIONQ1

ATHEROSCLEROSISQ1

Abstract

Background and aim: The prevalence of CARDIOVASCULAR DISEASEs have their roots in INFLAMMATION and systemic INFLAMMATION plays an important role in the development and progression of ATHEROSCLEROSIS. ICAM-1 is an indicator of inflammatory in the pathogenesis of ATHEROSCLEROSIS, which the effect of exercise and herbal remedies response are not well understood. The aim of the present study was to evaluate the high intensity aerobic interval training (HIIT) and flaxseed oil on ICAM-1 gene expression in heart tissue of male Wistar rats.Methods: Thirty Wistar rats were chosen and randomly divided into six groups of five including control, exercise, extracts dose of 10 mg/ kg, dose of 30 mg/kg of extract, extract exercise dose of 10 mg/kg and 30 mg extract mg/kg exercise groups. Group of exercise have done five sessions per week for 10 weeks, intense interval training consisted of running 90 to 95 percent VO2max intensity treadmill for rodents, at specified hours during the day. At the end of experiment the rats were sacrificed and heart tissue was prepared to measure gene expression of ICAM-1 and LFA-1.The data were analyzed by ANOVA statistical tests.Results: The data in the exercise group significantly reduced the expression of ICAM-1) p<0.039 and extract respectively. ITG also expressed in the exercise group (p<0.01) and extract decreased significantly. Data analysis showed that the expression of ICAM-1 has been reduced in training supplement groups.Conclusion: Compound exercises and flaxseed oil reduces the expression of ICAM-1 compared to control group, so it is likely that this method can be used as a way to prevent CARDIOVASCULAR DISEASE.

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APA: Copy

KHADEMI, Y., AZARBAYEJANI, M.A., & HOSSINI, A.. (2016). THE EFFECT OF HIGH INTENSITY AEROBIC INTERVAL TRAINING (HIIT) AND FLAXSEED OIL ON ICAM-1 GENE EXPRESSION IN HEART TISSUE OF MALE WISTAR RATS. ARMAGHAN DANESH, 21(9 (116)), 873-886. SID. https://sid.ir/paper/78128/en

Vancouver: Copy

KHADEMI Y., AZARBAYEJANI M.A., HOSSINI A.. THE EFFECT OF HIGH INTENSITY AEROBIC INTERVAL TRAINING (HIIT) AND FLAXSEED OIL ON ICAM-1 GENE EXPRESSION IN HEART TISSUE OF MALE WISTAR RATS. ARMAGHAN DANESH[Internet]. 2016;21(9 (116)):873-886. Available from: https://sid.ir/paper/78128/en

IEEE: Copy

Y. KHADEMI, M.A. AZARBAYEJANI, and A. HOSSINI, “THE EFFECT OF HIGH INTENSITY AEROBIC INTERVAL TRAINING (HIIT) AND FLAXSEED OIL ON ICAM-1 GENE EXPRESSION IN HEART TISSUE OF MALE WISTAR RATS,” ARMAGHAN DANESH, vol. 21, no. 9 (116), pp. 873–886, 2016, [Online]. Available: https://sid.ir/paper/78128/en

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