Yafteh
Year:2017 | Volume:19 | Issue:4 (73)|Papers Count:15

Background: Considering the importance of content and citation analysis in understanding the needs and improving journals’ scientific quality, the objective of the present study was to content and citation analysis of published articles in Lorestan University of Medical Sciences Journal (Yafte) during 2011 to 2015.Materials and Methods: This study is a prospective longitudinal study conducted in 2016.Published articles during 2011 to 2015 were studied. Data were collected by a researcher-made checklist and analyzed by SPSS version 21 and descriptive statistics.Results: Results showed that 95.8 percent of the articles were original and most of organizational affiliations of authors were related to Lorestan University of Medical Sciences (53.8). Over the past five years, 262 articles have been published in the Yafte Journal, half-life of resources were 8.38 years and the highest number of articles were published in the years 2013 and 2012.Conclusion: Considering the results of this study, it is suggested that the journal authorities should take necessary steps to balance organizational affiliations of published articles. It is also suggested that authors should be encouraged to use newer sources by setting some restrictions.

Background: This study aimed to investigate the effect of eight weeks of interval training on gene expression of liver X receptors (LXR) in Wistar male rats.Materials and Methods: In this study, 24 male wistar rats (200-250 g) were randomly used to three groups for this purpose, 24 male Wistar rats were prepared and divided into three groups: control (8 =n), high intensity intermittent exercise (8=n) and continuous submaximal exercise (8=n), respectively. The treadmill exercise program was performed for eight weeks, three days a week for 40 minutes. High intense exercise protocol, 30 minutes running periodic (every period of four minutes and two minutes running with 90-85% of VO2 max intensity active recovery with 60-50% of VO2 max) three days a week for eight weeks. Also, the continuous training group under maximum was an exercise intensity equivalent to 50 to 55 percent of maximum oxygen consumption of the mice.Results: The results showed that there was a significant difference between the four groups in the gene expression level, after data analysis and test research hypotheses, findings of this study show that the expression of LXR alpha gene, apolipoprotein 1, ABCG1 a significant increase in intensity interval exercise than the control group (p=0.004). The results also showed a significant difference between the three groups in the expression of LXR beta and apolipoprotein 2, SR-BI does not exist.Although the results showed a slight increase in groups of periodic training and continuing slight increase, but this has not led to a significant difference.Conclusion: Overall results indicated the superiority of intense interval training than submaximal exercise in reverse cholesterol transport is continuous. Intense interval training by increasing hepatic expression of the receptor gene as well as the main cause of the liver and eventually out HDL receptors can play an important role in reducing cardiovascular diseases such as atherosclerosis.

Background: The aim of this study was to predict the test anxiety and academic self-handicapping based on alexithymia in students with reading learning disorder.Materials and Methods: This study is a correlational study. The population included all of students with reading disorder in Khorramabad city in 2015-2016. Cohen’s Proposed Method was used for determining the size of the sample, and among the students who referred to education center in Kohrramabad, based on specialist's diagnosis in this field, in sum 112 students carried criteria for participating in this study. The students completed the test anxiety, self-handicapping and alexithymia questionnaires. Regression analysis was used for analyzing data. The data were analyzed by statistical SPSS software version 18.Results: The results showed that the correlation between study variables were significant (p>0.001).Also, The results of regression analysis showed that alexithymia was able to predict (54/. P<0.001) the total variance of test anxiety and academic self-handicapping.Conclusion: The results can help to counsolers and workers in the education field for effective interventions in test anxiety and academic self-handicapping.

Background: Latent autoimmune diabetes of adults (LADA) is a slowly progressive form of diabetes managed with diet and oral hypoglycemic agents before becoming insulin requiring. Islet autoantibodies are used for differential diagnosis between LADA and Type 2 diabetes mellitus. The aims of this study were to investigate the frequency of LADA using islet autontibodies in population with T2DM and characterize clinical and biochemical characteristics of them.Materials and methods: In this cross-sectional study, 86 T2DM patients aged between 28-67 years were tested for the presence of autoantibodies by ELISA technique. The Glutamic acid decarboxylase antibody, Islet Cell Antibody and Insulinoma Antigen2 Antibody were evaluated for diagnosis of LADA patients.Results: Of 86 T2DM, 35 (40.70%) were antibody positive and 51 (59.30%) persons were negative for any antibody. A significant difference was found between groups in age at study, insulin therapy, C- peptide levels and family history of autoimmune diseases. On the other hand, no significant difference was found between the two groups in other risk factors.Conclusions: Among our T2DM subjects, the number of LADA patients were not high. Also, multiple autoantibodies were more frequent than single autoantibodies in LADA patients.

Background: Some scientific data have been reported the positive effects of natural antioxidants on modulating the Total Antioxidant Capacity and muscular damage indicators.The aim of this research was to examine the effects of Short-Term Grapefruite juice Supplementation on Lipid Peroxidation and Total Antioxidant Capacity and some muscular damage indicators in young men following a session of intensive an resistanceactivity.Materials and Methods: In a randomized double-blind study twenty young men students were randomly divided into two equal groups of experimental, and control. After supplementation period, subjects performed a session of intensive resistance activity at 85% of one repetition maximum.Changes in the Total Antioxidant Capacity and malondialdehyde and muscular damage indicators (Lactate dehydrogenase and Creatine Kinase) were determined in three phases.Results: The results showed that changes in the Total Antioxidant Capacity and malondialdehyde after exercise not significantly in the supplementation group, but significantly in the control group.Also, changes in plasma Lactate dehydrogenase and Creatine Kinase after activity were significantly in the control and supplementation groups.Conclusion: It seems that Short-Term Grapefruit juice supplementation will be useful for improving levels of plasma Total Antioxidant Capacity and thereby inhibiting exercise-induced lipid peroxidation and modification in plasma increased Lactate dehydrogenase and Creatine Kinase after intensive resistance training.

Background: Type E hepatitis is a viral infectious disease, which affects the liver and can vary from an asymptomatic simple infection to a sudden-onset fatal disease, especially among pregnant women. The objective of the present study was to survey awareness and knowledge of general physicians working in Khorramabad in 2012.Materials and Methods: This is an epidemiological and descriptive study, which assesses physicians’ awareness of hepatitis E. The desired data were collected using questionnaires and the collected data were analyzed by descriptive statistical methods, such as tables of frequency distribution, cross-tabulations, means, standard variances, and ratios.Results: In the present study, 100 general physicians were surveyed, from among whom 62 physicians were male and 38 physicians were female. To assess the knowledge and awareness level of general physicians working in Khorramabad regarding hepatitis E, a 14-item questionnaire was designed. Their awareness and knowledge about the ways the disease is spread and about its prevalence levels was rather poor, but their knowledge regarding other aspects of the disease was moderate. No statistically significant difference was found between knowledge levels among male and female physicians. But, female physicians scored higher in items measuring awareness of prevention methods. The total knowledge score for physicians having practiced for less than 5 years was significantly different from physicians having more than 15 years of practice experience.Conclusion: General awareness level of general physicians working in Khorramabad regarding hepatitis E is moderate. Given an 8 percent prevalence level of this disease in Khorramabad and the high mortality rates due to the disease, especially among pregnant women and young people, more training is needed for general physicians.

Background: The studies show that the Diclofenac and Ibuprofen drugs influence cancer cells proliferation. The main aim of this study was to investigate the effects of Diclofenac and Ibuprofen on the viability of HEK cells in cell culture.Materials and Methods: In this laboratory experimental study, HEK cells were randomly divided into control group and groups exposed doses to 0.001, 0.01, 0.1, 10, 1 mg/ml of Ibuprofen and Diclofenac. The toxic effect of drugs was measured using the MTT assay method. The data were statistically analyzed between groups using ANOVA.Results: The viability of HEK cells exposed to 0.1, 0.01, 0.001 mg/ml of Ibuprofen was not significant increase in compared with control group. And the viability of HEK cells exposed to 1, 10, 0.1, 0.01, 0.001 mg/ml of Diclofenac significantly decreased compared to control group.(Classification P<0.01, P<0.01, P<0.01, P<0.05, P<0.01).Conclusion: Diclofenac and Ibuprofen in high doses destroy the HEK cells. Therefore, the use of these drugs in high doses is inappropriate.

Background: The rapid expansion of mass media, and in particular cyberspace, is one of the factors affecting people s health. Therefore, in this study, we investigated the life style affected by cyberspace and its effect on mental health.Materials and Methods: The method of the following study is a descriptive survey with purpose.The statistic groups are the university students of medical university of Lorestan between 2015 and 2016. To take samples we used the Cochran formula and the numbers of participants is 361 in a random order. In this study, to analysis the data, we use the descriptive statistics in two ways. The first part is descriptive statistics and in second part the analysis is done by inferential descriptive statistics. Data analysis was done by SPSS19 and Amos software.Results: The findings of this study are as follows: mean score of lifestyle influenced by the virtual space was not the same among sex, social-economic and marital status. There was also significant relationship between lifestyle and mental health is affected by the virtual space. The Structural Equation Model study was also approved the data is collected with the theoretical framework.Conclusion: Regarding the relationship between lifestyle and cyberspace and mental health it is recommended that authorities adopt programs that promote, expand and manage new mass media and thus enhance the mental health of students.

Background: The aim of this research was to investigate the effect of six months aerobic exercise with moderate intensity on BDNF, IL-6, and short-term memory in 50-65 years old women with syndrome metabolic.Materials and Methods: 24 women with metabolic syndrome (MetS) took part voluntarily and divided in tow groups MetS exercise (ME), MetS control (MC). ME group participated in an aerobic exercise training (AT) program (six months), tree session per week, each session containing tree performing part and tow rest part (five minutes). Initially, the duration of aerobic exercise in each session was eight minutes. One minute added each week to the duration of aerobic exercise till twelve weeks. Also, blood samples were conducted before and after six months training for evaluating levels of BDNF and IL-6. Short-term memory measured by Digit span memory test, BDNF, and IL-6 measured by Radioimmunoassay before and after six months aerobic training. Data were analyzed using Pearson coefficient, Pried-sample T-Test, and independent samples T-Test.Results: BDNF and short-term memory after six months aerobic exercise significantly increased (P˃0.05). IL-6 after six months aerobic exercise significantly decreased (P˃0.05).Conclusion: Findings show that six months aerobic exercises induce to decrease IL-6 and increase BDNF level, so this trend trepan ameliorate short-term memory score.

Background: Ibuprofen is a nonsteroidal anti-inflammatory medication of drugs that is used for relieving pain. However, this drug has proven effects, such as the production of free radicals and interfering with cellular events. Thus, it is necessary to find suitable antioxidants to reduce the side effects of this drug. In this study the antioxidant effects of cinnamon extract on the inhibition induced hepatoxicity of ibuprofen has been investigated.Materials and Methods: 48 rats in six groups, S group received saline solution, C200 group received cinnamon extract 200mg per kg body weight (200 mg/kg b.w), I group ibuprofen 400 mg/kg b.w, IC50 group ibuprofen together with cinnamon extract 50 mg/kg b.w, IC100 group ibuprofen together with cinnamon extract 100mg/kg b.w, IC200 group ibuprofen together with cinnamon extract 200 mg/kg b.w intraperitoneally. The activity of liver enzymes were measured in the end of the experimental period.Liver tissue sample was prepared and after staining with hematoxylin-eosin, was studied.Results: The activity of Pyruvate transaminase, oxaloacetate transaminase and alkaline phosphatase in I groupin comparison with S group were significantly increased. The activity of these enzymes in IC50, IC100 and IC200 groups in comparison with I group were significantly decreased nearly in a dose dependent manner. Examining the liver tissue indicate tissue damage caused by ibuprofen, and cinnamon consumption was reduced tissue destruction.Conclusion: Cinnamon extract has antioxidant properties and reduces the ibuprofen induced hepatoxicity.

Background: Emotional intelligence is a kind of emotional information processing which can protect individuals against substance abuse. The aim of this study was to investigate relation between emotional intelligence and addiction tendency.Materials and Methods: In this descriptive–analytic study, 240 students of Lorestan University of Medical Sciences, chosen based on the stage cluster sampling. Data was collected by demographic information and emotional intelligence (Brad Berry–Graves) questionnaire and addiction potential scale (APS) and were analyzed using Pearson regression, t-test and one-way ANOVA.Results: Mean score of addiction tendency was 28.47 and mean score of emotional intelligence (EQ) was 81.72. Findings of the research showed that there is a significant negative relationship between emotional intelligence and addiction tendency. In addition, based on Pearson analysis, there is a significant relationship between addiction tendency, self-awareness, social consciousness, self-management and relationship management subscales.Conclusion: people with a lower EQ have the higher tendency to substances abuse. EQ training programs can be used as a preventive factor for addiction.

Background: Musculoskeletal disorders are the main cause of loss of work time, increases in costs, and human injuries. Therefore, the investigation of the prevalence of these disorders among administrative employees needs to receive attention, given the long hours they work with computers and the way they sit at their desks.Materials and Methods: This cross-sectional study was conducted on the administrative employees of the Lorestan University of Medical Sciences working in Khorramabad, Iran. In addition to collecting the personal characteristics and demographic data of the participants, questions were asked about the meantime of using computers during the day, and the standard Nordic questionnaire was used to assess the prevalence of musculoskeletal disorders among the employees. To analyze the data, descriptive statistics were used to calculate the mean and standard deviation of each of the study variables. To analyze the relationships among the variables, the chi-squared test was used. All analyses were conducted using SPSS version 21.Results: The results of the study showed that the parts of the body most affected by the symptoms of musculoskeletal disorders were the upper back (60%), neck (59.4%), shoulders (50%), knees (49.4%), low back (47.1%), and wrist (42.4%) in order of prevalence. There were significant relationships between work experience with the prevalence of the symptoms in the shoulders, knees, thighs, ankles, and neck in the studied participants (p<0.05). However, no significant relationships were found in the areas of elbows, wrists, low back, and upper back. There was a significant relationship between the age of the employees and the occurrence of disorders in the elbows (p<0.05), such that the prevalence of disorders in this area increases with age, while increases in disorders in other areas of the body were not observed with age.Conclusion: Based on the results of the present study, musculoskeletal disorders are very frequently observed among administrative employees. In this regard, the implementation of ergonomic interventional programs in the work environment seems crucial. Some of the components of such a program can include training the users of computers regarding the ergonomic principles of working with computers, designing better workstations, and work shifts.

Background: Prostate cancer is the second most prevalent canceramong men and the eighth leading cause of death in Iran. In pathological conditions, angiogenesis increases the chance of metastasis and thus spreads cancer. The aim of the present study was to examine the effects of 10 weeks of resistance training on some angiogenesis factors among men affected by prostate cancer.Materials and Methods: Twenty men with prostate cancer aged between 55 and 62 were selected and randomly divided into control (n=10) and resistance training groups (n=10). The experimental group performed 10 weeks of resistance training, three sessions per week. Each exercise includes three sets of twelve repetitions with the intensity of 50-65 percent of 1RM. In order to measurement of NO, FGF and VEGF, blood samples were taken from the participants after 12 hours fasting state 24 hours before and 48 after the last training. For comparison of means between and within group' s independent and dependent T test were used, respectively.Results: The results showed that ten weeks of resistance training significantly increase the levels of VEGF (P=0.0001), FGF (P=0.0001) and NO (P=0.0003) in men suffering from prostate cancer.Conclusion: It appears 10 weeks of resistance training cause increase the level of angiogenesis factors, muscular strength and mass and decrease fatigue in men affected by prostate cancer.