This article discusses the mystical interpretation of Imam Khomeini's perspective in three areas: first, nature, second, principles, and third, method. Mystical Interpretation is a branch of commentary that deals with the intrinsic expression of the verses of the Qur'an and their codified meanings and is based on mystical taste and conduct and is achieved through discovery and intuition. In mystical interpretation, by accepting the appearance of the verses, the intentionality of the interpreter is to reach the inside of their verses, signs, and virtues, because the Qur'an has four layers: "Phrase", which belongs to the general, "Gesture", which is in the realm of perception. There are properties, "virtues", which are in the realm of understanding, and "facts", which are accessible to the prophets. The following is a reference to the history of mystical commentary. In the discussion of fundamentals, several axes have been put forward, which are briefly: the ontological basis; the basis of discovery knowledge; the linguistic basis. The basis of Quran enjoyment of descending order; The basis of Quran enjoyment of multiple semantic levels; The basis of understanding the Quran; The basis of inner purity. The Imam, while apparently praising the verses, has dealt with the mystical interpretation and considered the commentators' mission to discover the mystical intentions of the Qur'an.