Prevalence of Iron Overload in Patients with Multiple Sclerosis

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Alanazi Asma; Ogailan Ayah; Alnamassi Jenan; Alrakban Haya; Almutairi Taif; Almousa Nouf; Almalik Yaser; Eltaweel Asma

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal and Chemical Sciences Year:2023 | Volume:6 | Issue:11 Page(s): 2832-2840

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Prevalence of Iron Overload in Patients with Multiple Sclerosis

Author(s)

Keywords

Iron

Ferritin

Abstract

Background: Multiple sclerosis (MS) is a chronic autoimmune inflammatory condition results in dysfunction of the central nervous system. There are multiple causes linked to the development of MS disease including EBV exposure, vitamin D deficiency, and Iron overload. This study aiMS to examine the frequency of Iron overload in all multiple sclerotic patients with reported Iron serum levels at the National Guard Hospital (NGHA), Riyadh Center between 2015 and 2021.Materials and methods: A chart review based cross sectional retrospective study was conducted using the Best Care System Database, developed by NGHA, to estimate the prevalence of Iron overload in MS patients. Data were analyzed to identify the correlation between serum Iron and Ferritin levels with disease severity and activity, which were clinically assessed by the EDSS. The mean findings of blood analysis were also compared between males and females.Results: The findings of this study showed that there was no significant relationship between disease severity and elevated serum Iron and Ferritin level, with p-values of 0.130 and 0.856, respectively, 54.1% of the sample had an Iron level that was low/very low. The disability score of 20.3% of the sample affects their full daily activities. There was no significant difference between males and females in all means of blood analysis categories as P>0.05.Conclusion: Our study showed that the degree of disease severity and activity did not significantly correlate with the higher serum Iron levels (p-value of 0.130). Further study is needed to investigate the Iron level in the active MS plaques of the brain and spinal cord, and assess the severity in accordance to the sites of the specific plaques.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans