The recent development of dengue vaccine: A review

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Zainul Rahadian; Ansori Arif Nur Muhammad; Murtadlo Ahmad Affan Ali; Sucipto Teguh Hari; Kharisma Viol Dhea; Widyananda Muhammad Hermawan; Muchtaromah Bayyinatul; Fadholly Amaq; Kusala Muhammad Khaliim Jati; Jakhmola Vikash; Rebezov Maksim; Sahadewa Sukma; Wiradana Putu Angga

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Journal Paper

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Journal: Journal of Medicinal and Pharmaceutical Chemistry Research Year:2024 | Volume:6 | Issue:4 Page(s): 362-382

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Title

The recent development of dengue vaccine: A review

Author(s)

Keywords

dengueQ4

dengue virusQ4

MedicineQ4

VaccineQ4

Abstract

Dengue fever, caused by the dengue virus, is a significant global health concern, with millions of cases reported annually. The absence of specific antiviral treatments or effective preventive measures has fuelled the urgent need for a dengue Vaccine. This provides a comprehensive review of the development of a dengue Vaccine, summarizing the major milestones, challenges encountered, and recent advancements in this field. This study explores various Vaccine strategies employed, including live attenuated Vaccines, inactivated Vaccines, recombinant subunit Vaccines, and viral vector-based Vaccines. In addition, the manuscript discusses the clinical trials conducted to evaluate the safety and efficacy of these Vaccine candidates.

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