Assessing the safety of probiotic spray as an antibiotic alternative: A clinical trial at velayat burn injuries hospital

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Abootaleb Mohammad; Mohammadi Bandari Narjes; Karimli Mohammad; Mobayen Mohammadreza; Feizkhah Alireza; Masoumi Sanaz; Esmaeilzadeh Mojdeh; Bagheri Toolaroud Parissa

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Scientific Information Database

ISSN: 2588-4824

Journal Paper

Paper Information

Journal: Journal of Medicinal and Pharmaceutical Chemistry Research Year:2024 | Volume:6 | Issue:4 Page(s): 466-473

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Title

Assessing the safety of probiotic spray as an antibiotic alternative: A clinical trial at velayat burn injuries hospital

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Keywords

probioticsQ4

safetyQ4

clinical trialQ4

wounds and injuriesQ4

drug side effectsQ4

volunteersQ4

Abstract

It is crucial to find antibiotic alternatives and explore new chemicals and treatments. probiotics can produce a range of antimicrobial compounds, making them a viable substitute for antibiotics in preventing and treating bacterial infections. probiotics can produce various antimicrobial compounds such as organic acids, bacteriocins, hydrogen peroxide, diacetyl, and acetaldehyde. This experimental study aimed to assess the safety of a probiotic spray on participants receiving treatment at Velayat Burn Injuries Hospital in Rasht. A clinical trial was conducted to evaluate the safety of probiotic spray on healthy volunteers. The study involved ten healthy volunteers who visited Velayat Burn Injuries Hospital in 2023. Throughout the trial period, a standard checklist was used to review patient demographic information, prospective side effects, and assessments of local and systemic adverse events. According to the research, the probiotic spray that was under investigation showed no signs of causing any local or systemic reactions. The study suggests that it could be a possible option for treating second-degree burn wounds as it aids in promoting wound healing. In addition, showed use of probiotics as an alternative to antibiotics is a safer treatment option with fewer complications.

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