EFFECT 8-WEEKS ENDURANCE TRAINING ON THE BLOOD COAGULATION AND FIBRINOLYSIS SYSTEM RESPONSE TO EXHAUSTIVE TRAINING IN MALE RATS

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MALEKIZADEH F.; DABIDI ROUSHAN V.A.; HAJIZADEH MOGHADAM A.; FALAH MOHAMMADI ZIA

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Paper Information

Journal: JOURNAL OF APPLIED EXERCISE PHYSIOLOGY (JOURNAL OF SPORTS SCIENCE) Year:2009 | Volume:5 | Issue:9 Page(s): 65-75

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Title

EFFECT 8-WEEKS ENDURANCE TRAINING ON THE BLOOD COAGULATION AND FIBRINOLYSIS SYSTEM RESPONSE TO EXHAUSTIVE TRAINING IN MALE RATS

Author(s)

MALEKIZADEH F. | DABIDI ROUSHAN V.A. | HAJIZADEH MOGHADAM A. | FALAH MOHAMMADI ZIA | Issue Writer Certificate

Keywords

HAEMOSTATIC SYSTEMQ3

CARDIOVASCULAR DISEASEQ2

EXHAUSTIVE TRAININGQ3

RATSQ3

Abstract

The purpose of the present study was to detem1inethe etTect8 week’s endurance training on the blood coagulation and fibrinolysis system response to EXHAUSTIVE TRAINING in the young male RATS. Forty- eight RATS were divided randomly into control and experimental groups and subgroups. The experimental training programs were carried out for five days a week at the progressive treadmill with a defined speed and duration for eight weeks. EXHAUSTIVE TRAINING group performed 5 mins running with speed 20 m/min, 10 min with speed 25 m/min, and then with speed 30 m/min into exhaustion phase. Blood samples were drawn following 12 hours overnight fasting. The fibrinogen activated partial thromboplastin time (APTT) and plasminogen activator inhibitor (PAI-1) was measured by clotting and ELISA methods, respectively. Data was analyzed using two-way ANOVA with repeated measure and independent t-student tests. Statistical significance was accepted at P£0.05. The results showed the EXHAUSTIVE TRAINING has increased fibrinogen and APTT levels and decreased PAI-1 concentration. On the other hand, 8 week of endurance training lead to a decrease in fibrinogen (P£0.000) and APTT (P£0.049) levels in training group in comparison with control group. Furthermore, PAI-1 value was significant in training group in comparison with control group. Also, 8 weeks of endurance training induced significant changes in the resting fibrinogen (P£0.056), APTT (P£0.013) levels in training group in respect to control: These findings suggest the EXHAUSTIVE TRAINING causes coagulation system simulation and endurance training with moderate intensity can improved EXHAUSTIVE TRAINING-induced impairment on HAEMOSTATIC SYSTEM and prevent thrombus events.

Cites

INVESTIGATION RELATIONSHIP BETWEEN RESPIRATORY AND INFLAMMATORY MARKERS IN 14-16 YEAR’S OLD ACTIVE BOYS: EFFECT OF ON BOUT OF INCREMENTAL PHYSICAL ACTIVITY

References

THE EFFECTS OF ENDURANCE TRAINING ON SOME INDICES OF HAEMOSTATIC SYSTEM AND BLOOD LIPIDS IN THE AGED FEMALE RATS

Cite

APA: Copy

MALEKIZADEH, F., DABIDI ROUSHAN, V.A., HAJIZADEH MOGHADAM, A., & FALAH MOHAMMADI, ZIA. (2009). EFFECT 8-WEEKS ENDURANCE TRAINING ON THE BLOOD COAGULATION AND FIBRINOLYSIS SYSTEM RESPONSE TO EXHAUSTIVE TRAINING IN MALE RATS. JOURNAL OF APPLIED EXERCISE PHYSIOLOGY (JOURNAL OF SPORTS SCIENCE), 5(9), 65-75. SID. https://sid.ir/paper/129527/en

Vancouver: Copy

MALEKIZADEH F., DABIDI ROUSHAN V.A., HAJIZADEH MOGHADAM A., FALAH MOHAMMADI ZIA. EFFECT 8-WEEKS ENDURANCE TRAINING ON THE BLOOD COAGULATION AND FIBRINOLYSIS SYSTEM RESPONSE TO EXHAUSTIVE TRAINING IN MALE RATS. JOURNAL OF APPLIED EXERCISE PHYSIOLOGY (JOURNAL OF SPORTS SCIENCE)[Internet]. 2009;5(9):65-75. Available from: https://sid.ir/paper/129527/en

IEEE: Copy

F. MALEKIZADEH, V.A. DABIDI ROUSHAN, A. HAJIZADEH MOGHADAM, and ZIA FALAH MOHAMMADI, “EFFECT 8-WEEKS ENDURANCE TRAINING ON THE BLOOD COAGULATION AND FIBRINOLYSIS SYSTEM RESPONSE TO EXHAUSTIVE TRAINING IN MALE RATS,” JOURNAL OF APPLIED EXERCISE PHYSIOLOGY (JOURNAL OF SPORTS SCIENCE), vol. 5, no. 9, pp. 65–75, 2009, [Online]. Available: https://sid.ir/paper/129527/en

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