COMPARISON OF TOPICAL EFFECT OF MENTHA PIPERITA AND ROSMARINUS OFFICINALIS ESSENTIAL OILS ON INFECTED WOUND WHIT CANDIDA ALBICANS IN RAT

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FARAHPOUR M.R.; ASGHARI A.; FARHANGI GHALEJUOGHI N.; NEJATI H.

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Journal: JOURNAL OF VETERINARY MICROBIOLOGY Year:2016 | Volume:12 | Issue:2 (33) Page(s): 93-103

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Title

COMPARISON OF TOPICAL EFFECT OF MENTHA PIPERITA AND ROSMARINUS OFFICINALIS ESSENTIAL OILS ON INFECTED WOUND WHIT CANDIDA ALBICANS IN RAT

Author(s)

FARAHPOUR M.R. | ASGHARI A. | FARHANGI GHALEJUOGHI N. | NEJATI H. | Issue Writer Certificate

Keywords

MENTHA PIPERITAQ2

ROSMARINUS OFFICINALISQ2

CANDIDA ALBICANSQ1

INFECTED WOUND HEALINGQ1

Abstract

Wound infections caused by CANDIDA ALBICANS has grown substantially in recent years. Development of drug resistance led to the use of biological materials may be considered as an alternative solution. Studies show that MENTHA PIPERITA and ROSMARINUS OFFICINALIS contains flavonoids and menthol and hence they has antibacterial properties. We used sixty male Wistar rats (weight 195-205 g). One square surgical wound with dimensions of 1.5´1.5 cm were performed on the back of each animal and immediately became infected whit 0.1 ml of 1.5´107 CFU CANDIDA ALBICANS suspension. Then the rats were divided into 4 groups (control, placebo and Menthe piperita 3% ointment and ROSMARINUS OFFICINALIS 3% ointment) each with 15 rats and randomly distributed into 5 subgroups each whit 3 rats (sample groups on different days). Wound healing activity was performed by histological qualitative studies and yeast counts on the end of 4th, 8th, 12th, 16th and 20th days after surgery. Edema rate in treated groups in comparison with control and placebo groups significantly decreased (p<0.05). new blood formation, fibroblast migration, collagen deposition and reepithelization rate in comparison with control and placebo groups significantly increased (p<0.05). Topical application of MENTHA PIPERITA and ROSMARINUS OFFICINALIS accelerate CANDIDA ALBICANS INFECTED WOUND HEALING rate. This treatment option may be valuable in clinical practice.

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APA: Copy

FARAHPOUR, M.R., ASGHARI, A., FARHANGI GHALEJUOGHI, N., & NEJATI, H.. (2016). COMPARISON OF TOPICAL EFFECT OF MENTHA PIPERITA AND ROSMARINUS OFFICINALIS ESSENTIAL OILS ON INFECTED WOUND WHIT CANDIDA ALBICANS IN RAT. JOURNAL OF VETERINARY MICROBIOLOGY, 12(2 (33) ), 93-103. SID. https://sid.ir/paper/152190/en

Vancouver: Copy

FARAHPOUR M.R., ASGHARI A., FARHANGI GHALEJUOGHI N., NEJATI H.. COMPARISON OF TOPICAL EFFECT OF MENTHA PIPERITA AND ROSMARINUS OFFICINALIS ESSENTIAL OILS ON INFECTED WOUND WHIT CANDIDA ALBICANS IN RAT. JOURNAL OF VETERINARY MICROBIOLOGY[Internet]. 2016;12(2 (33) ):93-103. Available from: https://sid.ir/paper/152190/en

IEEE: Copy

M.R. FARAHPOUR, A. ASGHARI, N. FARHANGI GHALEJUOGHI, and H. NEJATI, “COMPARISON OF TOPICAL EFFECT OF MENTHA PIPERITA AND ROSMARINUS OFFICINALIS ESSENTIAL OILS ON INFECTED WOUND WHIT CANDIDA ALBICANS IN RAT,” JOURNAL OF VETERINARY MICROBIOLOGY, vol. 12, no. 2 (33) , pp. 93–103, 2016, [Online]. Available: https://sid.ir/paper/152190/en

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