EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS

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EIDI A.; MINAIEE TEHRANI D.; HATAMI M.

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Journal: BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN) Year:2009 | Volume:3 | Issue:4 Page(s): 1-7

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Information Journal Paper

Title

EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS

Author(s)

EIDI A. | MINAIEE TEHRANI D. | HATAMI M. | Issue Writer Certificate

Keywords

OLIVEQ2

DETOXIFICATIONQ2

LIVERQ2

RATQ2

ASTQ3

ALTQ3

Abstract

OLIVE (Olea europeae L.) is a tree that has been used as a hepatoprotective and antioxidant agent in traditional medicine. In present study, the protective effects of ethanolic extract of OLIVE leaves in RATs were evaluated. Wistar RATs were orally treated with OLIVE leaves extract (10, 100, 200 and 400 mg/kg) along with administration of CCl4 (50% CCl4/sunflower oil; 1ml/kg) for 28 days. The results showed that the treatment of OLIVE leaves extract significantly lowered the CCl4-induced serum levels of hepatic enzyme markers AST (aspartate amino transferase) and ALT (alanine amino transferase). Therefore, the results of the study suggest that the extract could protect LIVER against the CCl4-induced oxidative damage in RATs, and this hepatoprotective effect might be attributed to its modulation on DETOXIFICATION enzymes, its antioxidant and free radical scavenger effects.

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APA: Copy

EIDI, A., MINAIEE TEHRANI, D., & HATAMI, M.. (2009). EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS. BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN), 3(4), 1-7. SID. https://sid.ir/paper/183734/en

Vancouver: Copy

EIDI A., MINAIEE TEHRANI D., HATAMI M.. EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS. BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN)[Internet]. 2009;3(4):1-7. Available from: https://sid.ir/paper/183734/en

IEEE: Copy

A. EIDI, D. MINAIEE TEHRANI, and M. HATAMI, “EFFECT OF OLIVE LEAVES EXTRACT ON SERUM AST AND ALT LEVELS IN CCL4-INDUCED LIVER DAMAGE IN RATS,” BIOLOGICAL SCIENCES (DANISH-I ZISTI-I IRAN), vol. 3, no. 4, pp. 1–7, 2009, [Online]. Available: https://sid.ir/paper/183734/en

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