EFFECT OF CURCUMIN ON RAT EMBRYONIC NEUROPROGENITOR CELLS UNDER IN VITRO CONDITIONS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAJABI M.; PARIVAR K.; NABIOUNI M.; YAGHMAII P.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CELL & TISSUE Year:2014 | Volume:4 | Issue:4 Page(s): 435-443

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

821

Download:

Cites:

Information Journal Paper

Title

EFFECT OF CURCUMIN ON RAT EMBRYONIC NEUROPROGENITOR CELLS UNDER IN VITRO CONDITIONS

Author(s)

RAJABI M. | PARIVAR K. | NABIOUNI M. | YAGHMAII P. | Issue Writer Certificate

Keywords

ASTROCYTESQ2

CURCUMINQ2

NEUROPROGENITOR CELLSQ1

Abstract

Aim: CURCUMIN, a yellow pigment obtained from turmeric (Curcumina longa). It is a dietary polyphenol that has been reported to possess anticancer, anti-inflammatory, and antioxidant properties. CURCUMIN is potent radical scavenger and has key role in cell death prevention and because of its antioxidant ability, CURCUMIN has possible role in protection against neurodegenerative diseases. In this study we evaluate the effects of CURCUMIN on rat embryonic NEUROPROGENITOR CELLS viability and proliferation.Material and methods: In this study brain cortex of 15.5 day old embryos of Wistar rat dissected out and enzymaticaly dissociated to form single cell suspension. Cell suspension seeded in DMEM/F12 medium supplemented with N2, 1% antibiotic and mitogenes (10 ng.ml-1 EGF and 20 ng.ml-1 b-FGF). Cells were treated with different concentrations of CURCUMIN (0.1, 0.5, and 1mM). Cell viability was evaluated with MTT assay and immunocytochemical analysis was performed to evaluate astrocytic marker (GFAP). The data were analyzed with One-way ANOVA with Tukey’s post hoc test.Results: CURCUMIN (0.5 mM) enhanced ASTROCYTES neurite size (p<0.001) and also has significante effects on NEUROPROGENITOR CELLS differentiation in culture media.Conclusion: Data suggest that CURCUMIN enhanced NEUROPROGENITOR CELLS viability, growth and promoted differentiation of these cells in to ASTROCYTES.

Cites

No record.

References

No record.

Cite

APA: Copy

RAJABI, M., PARIVAR, K., NABIOUNI, M., & YAGHMAII, P.. (2014). EFFECT OF CURCUMIN ON RAT EMBRYONIC NEUROPROGENITOR CELLS UNDER IN VITRO CONDITIONS. JOURNAL OF CELL & TISSUE, 4(4), 435-443. SID. https://sid.ir/paper/188925/en

Vancouver: Copy

RAJABI M., PARIVAR K., NABIOUNI M., YAGHMAII P.. EFFECT OF CURCUMIN ON RAT EMBRYONIC NEUROPROGENITOR CELLS UNDER IN VITRO CONDITIONS. JOURNAL OF CELL & TISSUE[Internet]. 2014;4(4):435-443. Available from: https://sid.ir/paper/188925/en

IEEE: Copy

M. RAJABI, K. PARIVAR, M. NABIOUNI, and P. YAGHMAII, “EFFECT OF CURCUMIN ON RAT EMBRYONIC NEUROPROGENITOR CELLS UNDER IN VITRO CONDITIONS,” JOURNAL OF CELL & TISSUE, vol. 4, no. 4, pp. 435–443, 2014, [Online]. Available: https://sid.ir/paper/188925/en

Related Journal Papers