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Information Journal Paper

Title

PROTECTIVE EFFECT OF VITAMIN E ON SPERM PARAMETERS IN ADULT RAT TREATED WITH PARA-NONYLPHENOL

Pages

  415-424

Abstract

 Aim: The aim of this study was to investigate the effect of vitamin E on SPERM PARAMETERS in adult rat treated with PARA-NONYLPHENOL.Material and methods: Adult male rats were divided into four groups: Control, PARA-NONYLPHENOL, vitamin E and para-nonylphenl+vitamin E. Oral treatments were performed till 56 days. At the end of treatments, body and left testis weight were recorded and left caudal epididymis was cut in a medium. Released spermatozoa were used to analyze SPERM PARAMETERS such as sperm number, viability, morphology and motility. Sperm chromatin quality was assessed by nuclear staining using acridine orange and aniline blue.Results: Body and testis weight as well as normal sperm morphology showed no significant change in four groups. A significant decrease in the number, viability and motility of the sperm was found in rats treated by PARA-NONYLPHENOL compared to the control. This decrease was significantly compensated by vitamin E in PARA-NONYLPHENOL+vitamin E group compared to PARA-NONYLPHENOL group. The application of vitamin E alone could significantly increase sperm viability and motility as comared with the control. PARA-NONYLPHENOL had no effect on sperm DNA INTEGRITY and HISTON-PROTAMINE REPLACEMENT compared to the control.Conclusion: Vitamin E, as a potent antioxidant, could protect the adverse effect of PARA-NONYLPHENOL on certain SPERM PARAMETERS in adult rats.

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    APA: Copy

    MOMENI, H.R., & DANESHPAJOH, F.. (2012). PROTECTIVE EFFECT OF VITAMIN E ON SPERM PARAMETERS IN ADULT RAT TREATED WITH PARA-NONYLPHENOL. JOURNAL OF CELL & TISSUE, 2(4), 415-424. SID. https://sid.ir/paper/188953/en

    Vancouver: Copy

    MOMENI H.R., DANESHPAJOH F.. PROTECTIVE EFFECT OF VITAMIN E ON SPERM PARAMETERS IN ADULT RAT TREATED WITH PARA-NONYLPHENOL. JOURNAL OF CELL & TISSUE[Internet]. 2012;2(4):415-424. Available from: https://sid.ir/paper/188953/en

    IEEE: Copy

    H.R. MOMENI, and F. DANESHPAJOH, “PROTECTIVE EFFECT OF VITAMIN E ON SPERM PARAMETERS IN ADULT RAT TREATED WITH PARA-NONYLPHENOL,” JOURNAL OF CELL & TISSUE, vol. 2, no. 4, pp. 415–424, 2012, [Online]. Available: https://sid.ir/paper/188953/en

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