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Information Journal Paper

Title

ROLE OF RAPID URASE TEST IN COMPARISON WITH PCR FOR HELICOBACTER PYLORI INFECTION DIAGNOSIS

Pages

  31-36

Abstract

 Background and aim: H. PYLORI is a spiral shaped gram negative non invasive bacterium which causes peptic ulcer and has an important role in gastric carcinoma and MALT associated lymphoma. The aim of this research is to assess sensitivity and specificity of RAPID UREASE TEST in comparison with PCR.Material and Methods: 30 patients (test group) with peptic ulcer disease (PUD) and 30 patients (control group) with Non-Ulcer disease (NUD) were chosen from two centrers of endoscopy in Fars province during 2006. Endoscopy samples were examined by PCR and Rapid urase methods. In this study, PCR test is considered as golden standard test.Results: The assessment of infection sensitivity and specificity ,PPV and NPV RAPID UREASE TEST for the test group were detected 76.67%, 80.76%, 69.23%, 85.92%, 60.65% and in control group were 46.67%, 52.94%, 68.18%, 41.62% and 77.17% respectively.Conclusion: This study indicated that the Infection's rate, sensitivity and specificity of Rapid Urase test is acceptable in patients who are not under treatment. But the Infection's rate, sensitivity and specificity of Rapid Urase test is not acceptable in patients who are on Proton Pump Inhibitors (PPI) and treatment with antibiotic. So complementary tests in these patients are recommended.

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    APA: Copy

    KARGAR, MOHAMMAD, RAZAVIZADEGAN, S.H., ESHRAGHIAN, K., RAJPOUT, M.Y., GHORBANI DALINI, S., & KARGAR, MAHDI. (2009). ROLE OF RAPID URASE TEST IN COMPARISON WITH PCR FOR HELICOBACTER PYLORI INFECTION DIAGNOSIS. JOURNAL OF MICROBIAL WORLD, 2(1), 31-36. SID. https://sid.ir/paper/189162/en

    Vancouver: Copy

    KARGAR MOHAMMAD, RAZAVIZADEGAN S.H., ESHRAGHIAN K., RAJPOUT M.Y., GHORBANI DALINI S., KARGAR MAHDI. ROLE OF RAPID URASE TEST IN COMPARISON WITH PCR FOR HELICOBACTER PYLORI INFECTION DIAGNOSIS. JOURNAL OF MICROBIAL WORLD[Internet]. 2009;2(1):31-36. Available from: https://sid.ir/paper/189162/en

    IEEE: Copy

    MOHAMMAD KARGAR, S.H. RAZAVIZADEGAN, K. ESHRAGHIAN, M.Y. RAJPOUT, S. GHORBANI DALINI, and MAHDI KARGAR, “ROLE OF RAPID URASE TEST IN COMPARISON WITH PCR FOR HELICOBACTER PYLORI INFECTION DIAGNOSIS,” JOURNAL OF MICROBIAL WORLD, vol. 2, no. 1, pp. 31–36, 2009, [Online]. Available: https://sid.ir/paper/189162/en

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