EVALUATION OF RAPID UREASE TEST COMPARED WITH POLYMERASE CHAIN REACTION FOR DIAGNOSIS OF HELICOBACTER PYLORI

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PAKBAZ Z.; SHIRAZI M.H.; POURMAND M.R.; AZHDARKOSH H.; VAISE MALEKSHAHI Z.; AFSHAR D.; HAJIKHANI S.; MARDANI N.

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Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2014 | Volume:16 | Issue:6 Page(s): 394-400

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Title

EVALUATION OF RAPID UREASE TEST COMPARED WITH POLYMERASE CHAIN REACTION FOR DIAGNOSIS OF HELICOBACTER PYLORI

Author(s)

Keywords

HELICOBACTER PYLORIQ3

RAPID UREASE TESTQ3

PCRQ2

BIOPSYQ3

Abstract

Background: Current diagnostic methods for detecting HELICOBACTER PYLORI infection include RAPID UREASE TEST (RUT), urea breath test (UBT), histology, culture, and polymerase chain reaction (PCR). RUT is the most commonly method to diagnoseHELICOBACTER PYLORI infection because of its simple, rapid and accurate characters. The aim of this study is evaluation of RAPID UREASE TEST compared with PCR for diagnosis of HELICOBACTER PYLORI.Material and Methods: In this study 94 patients with dyspeptic symptoms attending the endoscopy suite of gastroenterology section of the Firouzgar University Hospital, Tehran, Iran, were enrolled. Patient’s antrum BIOPSY specimens were collected at endoscopy for the RAPID UREASE TEST and PCR. Data was recorded on a data sheet and analyzed using SPSS version 19.0. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of RUT was compared against PCR. The gold standard test for the diagnosis of HELICOBACTER PYLORI infection was PCR.Results: Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of RUT respectively were 97.2%, 89.2%, 81.4% and 98%.Conclusion: RUT has high sensitivity and specificity for detection of HELICOBACTER PYLORI infection.

Cites

EXPRESSION OF IL-18 CYTOKINE MRNA IN GASTRIC MUCOSA TISSUE OF PATIENTS WITH H. PYLORI INFECTION IN CHAHAR MAHAL AND BAKHTIARI

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APA: Copy

PAKBAZ, Z., SHIRAZI, M.H., POURMAND, M.R., AZHDARKOSH, H., VAISE MALEKSHAHI, Z., AFSHAR, D., HAJIKHANI, S., & MARDANI, N.. (2014). EVALUATION OF RAPID UREASE TEST COMPARED WITH POLYMERASE CHAIN REACTION FOR DIAGNOSIS OF HELICOBACTER PYLORI. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 16(6), 394-400. SID. https://sid.ir/paper/33886/en

Vancouver: Copy

PAKBAZ Z., SHIRAZI M.H., POURMAND M.R., AZHDARKOSH H., VAISE MALEKSHAHI Z., AFSHAR D., HAJIKHANI S., MARDANI N.. EVALUATION OF RAPID UREASE TEST COMPARED WITH POLYMERASE CHAIN REACTION FOR DIAGNOSIS OF HELICOBACTER PYLORI. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2014;16(6):394-400. Available from: https://sid.ir/paper/33886/en

IEEE: Copy

Z. PAKBAZ, M.H. SHIRAZI, M.R. POURMAND, H. AZHDARKOSH, Z. VAISE MALEKSHAHI, D. AFSHAR, S. HAJIKHANI, and N. MARDANI, “EVALUATION OF RAPID UREASE TEST COMPARED WITH POLYMERASE CHAIN REACTION FOR DIAGNOSIS OF HELICOBACTER PYLORI,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 16, no. 6, pp. 394–400, 2014, [Online]. Available: https://sid.ir/paper/33886/en

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