The Protective Effects of Royal Jelly on the Histomorphometric, Hormonal Alternation and Oxidative Stress in Ofloxacin Treated Male Rat

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EBADI MANAS GH.

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Journal: JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES) Year:2017 | Volume:10 | Issue:2 (37) Page(s): 83-93

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Title

The Protective Effects of Royal Jelly on the Histomorphometric, Hormonal Alternation and Oxidative Stress in Ofloxacin Treated Male Rat

Author(s)

EBADI MANAS GH. | Issue Writer Certificate

Keywords

OfloxacinQ1

Royal JellyQ1

RatQ1

HistomorphometricQ1

Oxidative StressQ1

Abstract

Inroduction & Objective: Royal Jelly is a compound that is produced by the worker honey bees. This compound has antioxidant activity and protective effects against Oxidative Stress. The aim of this study were to determine protective role of Royal Jelly on decrease side effects of Ofloxacin and return reproductive function near normal rang in Ofloxacin treated male Rat. Material and Methods: In this experimental work used 32 male albino Rats that each has body weight between 160-18o g and accidentally divided to 4 groups: Ofloxacin, Royal Jelly, Ofloxacin with Royal Jelly and control. Each group included 8 Rats. Dosage for Ofloxacin group was 216 mg/kg. BW Ofloxacin and for Royal Jelly group was 100 mg/kg. BW Royal Jelly. Royal Jelly with Ofloxacin group received 216 mg/kg Ofloxacin and100 mg/kg Royal Jelly. Control group received distilled water at dose of 216 mg/kg. BW. All groups received dose-related daily for 28 days orally. Data analyzed by one-way ANOVA and used Turkey HSD Post-test to compare the significance of difference. Results: After exposure Ofloxacin results revealed that diameter of seminiferous tubules, thickness of epithelium seminiferous tubules, weight testes, FSH, LH, testosterone, TTM, TAOC and RI in compared to control significance decline, but distance between seminiferous tubule, TDI, SI, MDA and NO significance increased. All parameters were improved to near normal rang level after exposure Royal Jelly. Conclusion: This investigation revealed that Ofloxacin has negative effect on histomorphometry and reproductive function in mature male Rats, but at the same time if you use Royal Jelly it is protects against Ofloxacin and retune to normal rang.

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APA: Copy

EBADI MANAS, GH.. (2017). The Protective Effects of Royal Jelly on the Histomorphometric, Hormonal Alternation and Oxidative Stress in Ofloxacin Treated Male Rat. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), 10(2 (37) ), 83-93. SID. https://sid.ir/paper/191677/en

Vancouver: Copy

EBADI MANAS GH.. The Protective Effects of Royal Jelly on the Histomorphometric, Hormonal Alternation and Oxidative Stress in Ofloxacin Treated Male Rat. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES)[Internet]. 2017;10(2 (37) ):83-93. Available from: https://sid.ir/paper/191677/en

IEEE: Copy

GH. EBADI MANAS, “The Protective Effects of Royal Jelly on the Histomorphometric, Hormonal Alternation and Oxidative Stress in Ofloxacin Treated Male Rat,” JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), vol. 10, no. 2 (37) , pp. 83–93, 2017, [Online]. Available: https://sid.ir/paper/191677/en

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