The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide

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Javan Masoomi f.; Talat Mehrabad j.; BABRI BONAB R.

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Journal: JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES) Year:2016 | Volume:9 | Issue:4 (35) Page(s): 43-53

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Title

The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide

Author(s)

Javan Masoomi f. | Talat Mehrabad j. | BABRI BONAB R. | Issue Writer Certificate

Keywords

Nanoparticles of Titanium DioxideQ1

Aloe veraQ1

Cardiovascular DiseaseQ1

MalondialdehydeQ1

Sialic Acid TomQ1

Troponin IQ1

Creatine Kinase MBQ1

Abstract

Inroduction & Objective: The effect of ethanol extraction of Aloe vera on certain biomarkers of Cardiovascular Disease in mice treated with titanium dioxide nanoparticles was studied. Material and Methods: Mice were received titanium dioxide nanoparticles with density of 100 milligrams per kg and ethanol extraction of Aloe vera plant with density of 100, 200 and 300 milligrams per kg for 30 days. Plasma levels ofMalondialdehyde, rich sialic acid, Troponin I and Creatine Kinase MB at the end of treatment was evaluated. The antioxidant activity of ethanol extraction in Aloe vera using free radical DPPH and total phenol levels were considered. Results: The results showed that giving titanium dioxide nanoparticles through the stimulation of oxidative activity had a significant increase in plasma levels of Malondialdehyde (MDA). Plasma levels of Troponin I, Creatine Kinase MB and rich sialic acid also significantly increased. With increasing density of Aloe vera, the total phenol and antioxidant activity of ethanol extraction increased. Giving the extraction significantly reduced the plasma levels of biomarkers of cardiovascular damage in mice treated with titanium dioxide nanoparticles. Conclusion: According to the results, ethanol extraction of Aloe vera as an antioxidant compound is able to reduce the levels of cardiovascular damage in mice treated with titanium dioxide nanoparticles.

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APA: Copy

Javan Masoomi, f., Talat Mehrabad, j., & BABRI BONAB, R.. (2016). The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), 9(4 (35) ), 43-53. SID. https://sid.ir/paper/191747/en

Vancouver: Copy

Javan Masoomi f., Talat Mehrabad j., BABRI BONAB R.. The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES)[Internet]. 2016;9(4 (35) ):43-53. Available from: https://sid.ir/paper/191747/en

IEEE: Copy

f. Javan Masoomi, j. Talat Mehrabad, and R. BABRI BONAB, “The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide,” JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), vol. 9, no. 4 (35) , pp. 43–53, 2016, [Online]. Available: https://sid.ir/paper/191747/en

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