THE EFFECT OF MORPHOLOGICAL AND STRUCTURAL OF PREGNANT NIH MICE’S OFFSPRING KIDNEY EXPOSURE TO HAIR DYE AND OXIDANT CREAM IN THIRD WEEK OF PREGNANCY

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SHARIFI SH.; SADOUGHI M.; AZARNIA M.

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Journal: JOURNAL OF DEVELOPMENTAL BIOLOGY Year:2009 | Volume:1 | Issue:2 Page(s): 59-64

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Title

THE EFFECT OF MORPHOLOGICAL AND STRUCTURAL OF PREGNANT NIH MICE’S OFFSPRING KIDNEY EXPOSURE TO HAIR DYE AND OXIDANT CREAM IN THIRD WEEK OF PREGNANCY

Author(s)

SHARIFI SH. | SADOUGHI M. | AZARNIA M. | Issue Writer Certificate

Keywords

HAIR DYEQ3

OXIDANT CREAMQ3

HISTOLOGYQ2

TERATOGENICQ2

EMBRYOTOXICQ3

MORPHOLOGICQ2

Abstract

Since the cosmetic products are the combination of several chemicals, and with due attention to harmful effects of them on offspring of pregnant females, on this research the effects of oxidative HAIR DYEs and their OXIDANT CREAMs were accomplished on kidneys of mice offspring that their mothers exposure to those products in third week of pregnancy.56 adult NIH mice (40 females, 16 males) were selected and after copulation and determination of pregnancy, pregnant females classified in 8 groups: exposure to 1 ml HAIR DYE in 2 successive days (2 doses), exposure to 1 ml OXIDANT CREAM in 2 successive days (2 doses), exposure to 1 ml HAIR DYE+1ml OXIDANT CREAM in 2 successive days (2 doses), exposure to 1 ml HAIR DYE in 4 successive days (4 doses), exposure to 1ml OXIDANT CREAM in 4 successive days (4 doses), exposure to 1ml HAIR DYE+1ml OXIDANT CREAM in 4 successive days (4 doses), stressful control and non stress control.30 offspring were selected randomaly from every group and after MORPHOLOGICal studies and statistical analysis the results with one sided variance analysis method, their kidney tissues were extract and studied by light microscope after fixation in formalin and staining with Hematoxylin and Eosin (paraffin section- H & E).Without any MORPHOLOGICal differences, we observed a decrease in weight, length of body, length of hand and foot and also a decrease in nephronic concentration in kidneys medulla and nephronic disorder in kidneys cortex in high dosage (specially in 4 doses OXIDANT CREAM group). In fact HAIR DYEs can modulate the harmful effects of OXIDANT CREAMs to some extent.

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APA: Copy

SHARIFI, SH., SADOUGHI, M., & AZARNIA, M.. (2009). THE EFFECT OF MORPHOLOGICAL AND STRUCTURAL OF PREGNANT NIH MICE’S OFFSPRING KIDNEY EXPOSURE TO HAIR DYE AND OXIDANT CREAM IN THIRD WEEK OF PREGNANCY. JOURNAL OF DEVELOPMENTAL BIOLOGY, 1(2), 59-64. SID. https://sid.ir/paper/193095/en

Vancouver: Copy

SHARIFI SH., SADOUGHI M., AZARNIA M.. THE EFFECT OF MORPHOLOGICAL AND STRUCTURAL OF PREGNANT NIH MICE’S OFFSPRING KIDNEY EXPOSURE TO HAIR DYE AND OXIDANT CREAM IN THIRD WEEK OF PREGNANCY. JOURNAL OF DEVELOPMENTAL BIOLOGY[Internet]. 2009;1(2):59-64. Available from: https://sid.ir/paper/193095/en

IEEE: Copy

SH. SHARIFI, M. SADOUGHI, and M. AZARNIA, “THE EFFECT OF MORPHOLOGICAL AND STRUCTURAL OF PREGNANT NIH MICE’S OFFSPRING KIDNEY EXPOSURE TO HAIR DYE AND OXIDANT CREAM IN THIRD WEEK OF PREGNANCY,” JOURNAL OF DEVELOPMENTAL BIOLOGY, vol. 1, no. 2, pp. 59–64, 2009, [Online]. Available: https://sid.ir/paper/193095/en

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