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Information Journal Paper

Title

EFFECTIVENESS OF MALVA SYLVESTRIS EXTRACT ON GROWTH AND BIOFILMFORMATION OF PSEUDOMONAS AERUGINOSA

Pages

  33-39

Abstract

 Aim and Background: PSEUDOMONAS AERUGINOSA is an important opportunistic pathogen that typically makes a BIOFILM. P. aeruginosabiofilms are intrinsically resistant to antimicrobial chemotherapies. The aim of this study was to evaluate theinhibitory effects of ethanolic extract of MALVA SYLVESTRIS on the BIOFILM formation of Pseudomonasaeruginosa ATCC: 27853. Material and methods: The alcoholic extracts of MALVA SYLVESTRIS which were collected from north western Iran(Kurdistan)were obtainedby soxhlet apparatus. The antibacterial effect of plant extract was determined by well diffusion agar. The minimalinhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were assessed by MICro dilutionmethod according to CLSL standard. Finally BIOFILM formation of these this strain in presence of ethanolic extract of M. sylvestris was determinedusing modified MICro titer plate method. Statistic analysis was done by t-test and analysis ofvariance(ANOVA) was used to compare means and data correlation. Results: The results showed a significant effect of ethanolic extract of M. sylvestris on the tested strain. The MIC andMBC were 62. 5 mg ⁄ ml. The different concentration of ethanolic extract of M. sylvestris decreasedsignificantly in BIOFILM formation. on P. aeruginosa in compared to gentamicin as the positive control (P value =0. 0124). Conclusion: According to the finding MALVA SYLVESTRIS, is effective in killing P. aeruginosa. bacterial biofim so thismedicinal plant appears to be promising agent for prophylaxis against various pseudomonas infections.

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    APA: Copy

    AMINNEZHAD, SARGOL, KASRA KERMANSHAHI, ROHA, MIRZAI, MORTEZA, & RASHIDIANI, JAMAL. (2017). EFFECTIVENESS OF MALVA SYLVESTRIS EXTRACT ON GROWTH AND BIOFILMFORMATION OF PSEUDOMONAS AERUGINOSA. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 7(28 ), 33-39. SID. https://sid.ir/paper/204491/en

    Vancouver: Copy

    AMINNEZHAD SARGOL, KASRA KERMANSHAHI ROHA, MIRZAI MORTEZA, RASHIDIANI JAMAL. EFFECTIVENESS OF MALVA SYLVESTRIS EXTRACT ON GROWTH AND BIOFILMFORMATION OF PSEUDOMONAS AERUGINOSA. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2017;7(28 ):33-39. Available from: https://sid.ir/paper/204491/en

    IEEE: Copy

    SARGOL AMINNEZHAD, ROHA KASRA KERMANSHAHI, MORTEZA MIRZAI, and JAMAL RASHIDIANI, “EFFECTIVENESS OF MALVA SYLVESTRIS EXTRACT ON GROWTH AND BIOFILMFORMATION OF PSEUDOMONAS AERUGINOSA,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 7, no. 28 , pp. 33–39, 2017, [Online]. Available: https://sid.ir/paper/204491/en

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