dentifying antibiotic resistance genes in clinical isolates of Klebsiella pneumoniae producing IMP-1 and TEM β-lactamase

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GOODARZI LEILA; YARI REZA; MIRZAEI MOHSEN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2019 | Volume:9 | Issue:35 Page(s): 25-34

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Information Journal Paper

Title

dentifying antibiotic resistance genes in clinical isolates of Klebsiella pneumoniae producing IMP-1 and TEM β-lactamase

Author(s)

GOODARZI LEILA | YARI REZA | MIRZAEI MOHSEN | Issue Writer Certificate

Keywords

Klebsiella pneumoniaQ1

Extended-Spectrum Betalactamase (ESBL)Q1

TEMQ1

IMP-1Q1

Antibiotic ResistanceQ2

Abstract

Aim &Background: Klebsiella pneumoniae is a common cause of β-lactamase-associated infections in hospitals. The present study aimed to determine the frequency of Antibiotic Resistance genes in Klebsiella pneumoniae strains producing IMP-1 and TEM β-lactamase. Materials and methods: The present research identified 94 samples of K. pneumoniae, using antibiogram for the phenotypic confirmation of ESBLs. The Antibiotic Resistance of the isolates and the prevalence of TEM and IMP-1 genes were determined using PCR method. Findings: Of 94 samples, 77. 6% were ESBL-positive and 22. 3% ESBL-negative. A total of 4. 1% of the samples carried the IMP-1 gene and 43. 8% the TEM gene, while 43. 8% of the samples carried both genes. Conclusion: Given that TEM and IMP-1 genes were commonly present in a large number of the resistant samples, physicians are recommended to use therapeutic measures properly, and to prescribe antibiotics rationally.

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APA: Copy

GOODARZI, LEILA, YARI, REZA, & MIRZAEI, MOHSEN. (2019). dentifying antibiotic resistance genes in clinical isolates of Klebsiella pneumoniae producing IMP-1 and TEM β-lactamase. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 9(35 ), 25-34. SID. https://sid.ir/paper/204513/en

Vancouver: Copy

GOODARZI LEILA, YARI REZA, MIRZAEI MOHSEN. dentifying antibiotic resistance genes in clinical isolates of Klebsiella pneumoniae producing IMP-1 and TEM β-lactamase. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2019;9(35 ):25-34. Available from: https://sid.ir/paper/204513/en

IEEE: Copy

LEILA GOODARZI, REZA YARI, and MOHSEN MIRZAEI, “dentifying antibiotic resistance genes in clinical isolates of Klebsiella pneumoniae producing IMP-1 and TEM β-lactamase,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 9, no. 35 , pp. 25–34, 2019, [Online]. Available: https://sid.ir/paper/204513/en

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