DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF NONTUBERCULOUS MYCOBACTERIA FROM IRANIAN PATIENTS

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HEIDARIEH PARVIN; KHOSRAVI AZAR DOKHT; HASHEMI SHAHRAKI ABDOLRAZAAGH; ZAKERBOSTANABAD SAIED; NASHIBI ROOHANGIZ; KHANDAN DEZFULI SOLMAZ; ETEMAD NAYEREH; AHMAD KHOSRAVI NAZANIN; ABBASPOUR ARMAGHAN; HASHEMZADEH MOHAMMAD

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Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2016 | Volume:6 | Issue:22 Page(s): 9-15

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Title

DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF NONTUBERCULOUS MYCOBACTERIA FROM IRANIAN PATIENTS

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Keywords

NON-TUBERCULOUS MYCOBACTERIAQ1

MICRO BROTH DILUTIONQ1

SUSCEPTIBILITY TESTINGQ1

IRANNEWQ2

Abstract

Aim and Background: NON-TUBERCULOUS MYCOBACTERIA have long been identified as capable of causing human disease. Several reports have suggested increasing trend to available treatment regimes. The aim of this study was to evaluate antibiotic susceptibility of clinically significant NTM using standard MICRO BROTH DILUTION test.Material and methods: The antimicrobial SUSCEPTIBILITY TESTING was performed following National Committee for Clinical Laboratory Standards (NCCLS) method for 88 clinical isolates of slowly growing mycobacteria (SGM) and 154 clinical isolates of rapidly growing mycobacteria (RGM).Results: Among the 40 isolates of M. kansasii, all were susceptible to Ethambutol, Isoniazid, Clarithromycin, Moxifloxacin and Linezolid. The isolates also were resistant to Doxycycline and 50% isolates were resistant to Rifampicin and Ciprofloxacin.Conclusion: The presence of high variations in susceptibility among clinically important NTM to the currently available antimicrobial agents confirms the need for accurate identification as well as performing standard SUSCEPTIBILITY TESTING of any clinically important isolate.

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APA: Copy

HEIDARIEH, PARVIN, KHOSRAVI, AZAR DOKHT, HASHEMI SHAHRAKI, ABDOLRAZAAGH, ZAKERBOSTANABAD, SAIED, NASHIBI, ROOHANGIZ, KHANDAN DEZFULI, SOLMAZ, ETEMAD, NAYEREH, AHMAD KHOSRAVI, NAZANIN, ABBASPOUR, ARMAGHAN, & HASHEMZADEH, MOHAMMAD. (2016). DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF NONTUBERCULOUS MYCOBACTERIA FROM IRANIAN PATIENTS. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 6(22), 9-15. SID. https://sid.ir/paper/204619/en

Vancouver: Copy

HEIDARIEH PARVIN, KHOSRAVI AZAR DOKHT, HASHEMI SHAHRAKI ABDOLRAZAAGH, ZAKERBOSTANABAD SAIED, NASHIBI ROOHANGIZ, KHANDAN DEZFULI SOLMAZ, ETEMAD NAYEREH, AHMAD KHOSRAVI NAZANIN, ABBASPOUR ARMAGHAN, HASHEMZADEH MOHAMMAD. DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF NONTUBERCULOUS MYCOBACTERIA FROM IRANIAN PATIENTS. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2016;6(22):9-15. Available from: https://sid.ir/paper/204619/en

IEEE: Copy

PARVIN HEIDARIEH, AZAR DOKHT KHOSRAVI, ABDOLRAZAAGH HASHEMI SHAHRAKI, SAIED ZAKERBOSTANABAD, ROOHANGIZ NASHIBI, SOLMAZ KHANDAN DEZFULI, NAYEREH ETEMAD, NAZANIN AHMAD KHOSRAVI, ARMAGHAN ABBASPOUR, and MOHAMMAD HASHEMZADEH, “DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF NONTUBERCULOUS MYCOBACTERIA FROM IRANIAN PATIENTS,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 6, no. 22, pp. 9–15, 2016, [Online]. Available: https://sid.ir/paper/204619/en

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