EXAMINATION OF THE CRATAEGUS EXTRACT EFFECT ON PASSIVE AVOIDANCE LEARNING OF MALE WISTAR RAT

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TAHMASEBI SAEED; HEIDARIEH NASRIN; MOHAJERANI HAMID REZA

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Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2013 | Volume:3 | Issue:12 Page(s): 79-86

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Title

EXAMINATION OF THE CRATAEGUS EXTRACT EFFECT ON PASSIVE AVOIDANCE LEARNING OF MALE WISTAR RAT

Author(s)

TAHMASEBI SAEED | HEIDARIEH NASRIN | MOHAJERANI HAMID REZA | Issue Writer Certificate

Keywords

CRATAEGUS EXTRACTQ2

PASSIVE AVOIDANCE LEARNINGQ2

RATQ2

FLAVONOIDQ1

Abstract

Aim and Background: Epidemiological and experimental studies of animals indicated that FLAVONOID rich diets can affect positively on decrease of the prevalence of neuronal degenerations e.g. Alzheimer and Parkinsonism diseases. In the basis of the positive function of CRATAEGUS EXTRACT on decrease of oxidative factors and other helpful characteristics of this extract, the present research examined CRATAEGUS EXTRACT effect on PASSIVE AVOIDANCE LEARNING of male wistar RAT.Materials and methods: 24 RATs with 250-300 gram weight were divided into three main groups: 1- control (intact) 2- sham (solvent receivers) 3- CRATAEGUS EXTRACT. The extract was administered daily (100mg/kg) for two weeks by gavages’ method. PASSIVE AVOIDANCE LEARNING test was conducted by shuttle box system. One day after acquisition, retrieval test was done. For this, the animals were placed in a light compartment and after 30 seconds guillotine door were opened and the time that was consumed for entering to dark component was recorded. Data were analyzed by SPSS software with one way ANOVA and Tuckey test.Results: The results indicated that there is no difference between intact and sham groups at the time of entering to dark component but there was significant increase between extract and intact groups (P<0.001) and decrease between them for entering dark component (P<0.001).Conclusion: Results of this study showed that treatment by CRATAEGUS EXTRACT that is FLAVONOID rich, resulted in the recovery of learning and memory.

Cites

Effect of hydroalcoholic chamomile (Atricaria chamomilla) extract on avoidance memory

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APA: Copy

TAHMASEBI, SAEED, HEIDARIEH, NASRIN, & MOHAJERANI, HAMID REZA. (2013). EXAMINATION OF THE CRATAEGUS EXTRACT EFFECT ON PASSIVE AVOIDANCE LEARNING OF MALE WISTAR RAT. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 3(12), 79-86. SID. https://sid.ir/paper/204683/en

Vancouver: Copy

TAHMASEBI SAEED, HEIDARIEH NASRIN, MOHAJERANI HAMID REZA. EXAMINATION OF THE CRATAEGUS EXTRACT EFFECT ON PASSIVE AVOIDANCE LEARNING OF MALE WISTAR RAT. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2013;3(12):79-86. Available from: https://sid.ir/paper/204683/en

IEEE: Copy

SAEED TAHMASEBI, NASRIN HEIDARIEH, and HAMID REZA MOHAJERANI, “EXAMINATION OF THE CRATAEGUS EXTRACT EFFECT ON PASSIVE AVOIDANCE LEARNING OF MALE WISTAR RAT,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 3, no. 12, pp. 79–86, 2013, [Online]. Available: https://sid.ir/paper/204683/en

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