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Information Journal Paper

Title

EVALUATION OF EMBRYO PRODUCTION POTENCY IN FOUR LABORATORY MICE STRAINS IN RESPONSE TO GONADOTROPIN HORMONES

Pages

  688-693

Abstract

 To identify the suitable lab mouse with more potency in EMBRYO production, four commonly used strains of laboratory mice as NIH, NMRI, Balb/c and (Balb/c×NMRI) F1 were used in this experiment. One hundred and five mice of 7-8 weeks old were randomly selected from four strains and divided in 9 groups of 10 mice and 3 groups of 5 mice. Mice in group 2, 5, 8 & 11, received 5 IU and group 3, 6, 9 & 12 received 10 IU PMSG and HCG hormones intraperitonaly, group 1, 4, 7 & 10 were assigned as controls.Mice of all groups mated with their strain by trios. Results show mice which received 5 IU hormones, have respectively produced 9.5, 9.8, 38.6 & 34.8 EMBRYOs and other group of 10 IU, had 7.3, 11.4, 39.7 & 37.3 EMBRYO. Number of EMBRYOs in Balb/c strain of group 8 with 9 in P<0.001 and also in F1 group 11 with 10 in P<0.05 were significantly different. In intergroup comparison, groups 2 & 5 with groups 8 & 11, also 9 with 3 & 6 there was significant difference. However NIH & NMRI strains were graded in low ovulators mice and Balb/c and F1 graded in high ovulators. Additionally, pronuclars in F1 EMBRYOs were very prominent. Results suggest the Balb/c strain is the most suitable mice for EMBRYO production in comparison with the other strain worked in this study.

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    APA: Copy

    TODEHDEHGHAN, F., & MOTEDAYEN, M.H.. (2011). EVALUATION OF EMBRYO PRODUCTION POTENCY IN FOUR LABORATORY MICE STRAINS IN RESPONSE TO GONADOTROPIN HORMONES. IRANIAN JOURNAL OF BIOLOGY, 24(5), 688-693. SID. https://sid.ir/paper/21294/en

    Vancouver: Copy

    TODEHDEHGHAN F., MOTEDAYEN M.H.. EVALUATION OF EMBRYO PRODUCTION POTENCY IN FOUR LABORATORY MICE STRAINS IN RESPONSE TO GONADOTROPIN HORMONES. IRANIAN JOURNAL OF BIOLOGY[Internet]. 2011;24(5):688-693. Available from: https://sid.ir/paper/21294/en

    IEEE: Copy

    F. TODEHDEHGHAN, and M.H. MOTEDAYEN, “EVALUATION OF EMBRYO PRODUCTION POTENCY IN FOUR LABORATORY MICE STRAINS IN RESPONSE TO GONADOTROPIN HORMONES,” IRANIAN JOURNAL OF BIOLOGY, vol. 24, no. 5, pp. 688–693, 2011, [Online]. Available: https://sid.ir/paper/21294/en

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