IMMUNOMODULATORY EFFECTS OF POMEGRANATE JUICE, DATE PALM AND FIG FRUITS ON PREVENTION AND TREATMENT OF EXPERIMENTAL ACUTE COLITIS MODEL IN MALE RAT

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ZANGENEH Z.F.; ABDOLLAHI A.R.; NAGHIZADEH M.M.; AMINEE F.

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Journal: IRANIAN JOURNAL OF BIOLOGY Year:2012 | Volume:25 | Issue:3 Page(s): 396-408

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Title

IMMUNOMODULATORY EFFECTS OF POMEGRANATE JUICE, DATE PALM AND FIG FRUITS ON PREVENTION AND TREATMENT OF EXPERIMENTAL ACUTE COLITIS MODEL IN MALE RAT

Author(s)

ZANGENEH Z.F. | ABDOLLAHI A.R. | NAGHIZADEH M.M. | AMINEE F. | Issue Writer Certificate

Keywords

INFLAMMATORY BOWEL DISEASE (IBD)Q2

INTERLEUKIN-6Q2

TUMOUR NECROSIS FACTORALPHAQ2

Abstract

Inflammatory bowel diseases (IBD) are the one of the most comment alimentary diseases. Etiology and pathogenesis of IBD remain obscure. There is substantial evidence that proinflammatory cytokines such as INTERLEUKIN-6 (IL-6) and Tumour Necrosis Factor-alpha (TNF-alpha) exhibit a key role in the inflammatory process. In the last decade investigations were done on treatment and pretreatment effects of some modulators and inhibitors of these mediators which emphasize different aspects of experimental colitis models mimicking IBD in human. The aim of this study is investigation of therapeutic and prophylactic effects of pomegranate, fig and date in daily regimen in experimental acute colitis model on rat. The results of this study show that pomegranate juice induces both therapeutic and prophylactic effects and date has only therapeutic effect on colitis.

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References

THE EFFECT OF PALM DATE, FIG AND OLIVE FRUITS REGIMEN ON WEIGHT, PAIN THRESHOLD AND MEMORY IN MICE

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APA: Copy

ZANGENEH, Z.F., ABDOLLAHI, A.R., NAGHIZADEH, M.M., & AMINEE, F.. (2012). IMMUNOMODULATORY EFFECTS OF POMEGRANATE JUICE, DATE PALM AND FIG FRUITS ON PREVENTION AND TREATMENT OF EXPERIMENTAL ACUTE COLITIS MODEL IN MALE RAT. IRANIAN JOURNAL OF BIOLOGY, 25(3), 396-408. SID. https://sid.ir/paper/21456/en

Vancouver: Copy

ZANGENEH Z.F., ABDOLLAHI A.R., NAGHIZADEH M.M., AMINEE F.. IMMUNOMODULATORY EFFECTS OF POMEGRANATE JUICE, DATE PALM AND FIG FRUITS ON PREVENTION AND TREATMENT OF EXPERIMENTAL ACUTE COLITIS MODEL IN MALE RAT. IRANIAN JOURNAL OF BIOLOGY[Internet]. 2012;25(3):396-408. Available from: https://sid.ir/paper/21456/en

IEEE: Copy

Z.F. ZANGENEH, A.R. ABDOLLAHI, M.M. NAGHIZADEH, and F. AMINEE, “IMMUNOMODULATORY EFFECTS OF POMEGRANATE JUICE, DATE PALM AND FIG FRUITS ON PREVENTION AND TREATMENT OF EXPERIMENTAL ACUTE COLITIS MODEL IN MALE RAT,” IRANIAN JOURNAL OF BIOLOGY, vol. 25, no. 3, pp. 396–408, 2012, [Online]. Available: https://sid.ir/paper/21456/en

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