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Information Journal Paper

Title

Investigation of antioxidant, anti-bacterial properties and binding to humanserum albumin in the Cressa cretica L. grown in the Sistan region

Pages

  11-20

Abstract

 Cressa cretica L., due to producing of some various compounds, which could be used as asource of many herbal medicines. The present research were studied in Antioxidant, Antibacterialproperties and the ability of interaction with human serum albumin (HSA) of Cressa cretica L. So the leaves of the plant were collected in vegetative stage from Sistan in 2015. Three kinds ofextraction such as aquatic, methanolic and ethanolic extracts were obtained by using macerationmethod. The Antioxidant activity were measured by DPPH method. The interaction of ethanolicextraction with HSA was performed by UV-Vis spectroscopy. The Anti-bacterial properties ofextracts against Staphylococcus aureus, and Escherichia coli were investigated by MIC andMBC methods. The results were showed that the lowest and highest Extraction efficiency wererelated to the aquatic and ethanolic, respectively. The ethanolic extract had the highestantioxidant activity in inhibition percentage of DPPH than other extracts (56, 38 and 34%)respectively. Study of the interaction with HSA demonstrated the changes in protein secondarystructure and the binding constant in that obtained 0. 49 × 102 ppm-1. This plant showedacceptable bactericidal activity and MIC values were higher than the MBC.

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    APA: Copy

    SHAHRAKI, S., & SHAHRAKI, T.. (2018). Investigation of antioxidant, anti-bacterial properties and binding to humanserum albumin in the Cressa cretica L. grown in the Sistan region. ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, 6(1 (21) ), 11-20. SID. https://sid.ir/paper/247786/en

    Vancouver: Copy

    SHAHRAKI S., SHAHRAKI T.. Investigation of antioxidant, anti-bacterial properties and binding to humanserum albumin in the Cressa cretica L. grown in the Sistan region. ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS[Internet]. 2018;6(1 (21) ):11-20. Available from: https://sid.ir/paper/247786/en

    IEEE: Copy

    S. SHAHRAKI, and T. SHAHRAKI, “Investigation of antioxidant, anti-bacterial properties and binding to humanserum albumin in the Cressa cretica L. grown in the Sistan region,” ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, vol. 6, no. 1 (21) , pp. 11–20, 2018, [Online]. Available: https://sid.ir/paper/247786/en

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