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Title

ANTIOXIDANT ACTIVITY, PHYTOCHEMICAL AND ETHNOPHARMACOLOGY OF MELILOTUS OFFICINALIS L. AS ANTI INFLAMMATORY TO TREAT OF DIABETIC SORE (SHORT PAPER)

Author(s)

KHAKI A. | Issue Writer Certificate 

Pages

  73-81

Abstract

 Melilotus officinalis L. belongs to Fabaceae family, is a annual medicinal herb which has been used by the rural people of Iran as antiseptic, sedative and antispasmodic. This purpose study conducted in investigation of phenolic, flavonoid compounds and antioxidant activity content of ethanolic extract of Melilotus officinalis L. in Gorgan region. Aerial parts of Melilotus officinalis L. in blooming, were collected in May 2014 (15 m), the most important ethnopharmocological data were obtained from the rural people. The ethanolic extract was obtained by maceration and the TOTAL PHENOL (TP), TOTAL FLAVONOID (TF) and total anthocyanin (TA) contents were obtained by spectrophotometry and antioxidant activity were measured by 3 methods (DPPH, TAC and RP) in IC50 content, in three replications and the results expressed as mean±SD. Melilotus officinalis L. was the natural medicinal plant which wild growing in grassland regions in Semi halin Soil, which has been used by rural as powerful antiseptic and anti-inflammatory. TP content (109.8±0.4mgGAE/g) and TF (82±0.2mgQUE/g) content were reported and followed by the highest antioxidant activity with IC50 (3.17±0.2 ϻg/ml) especially in DPPH test in 1% level. Also with increase of concentration of extract was increased antioxidant activity. The high quality of secondary metabolites (TP, TF) and efficient performance of antioxidant activity would be confirmed traditional uses of the plant as antiseptic. So suggested further studies performed to investigation for anti bacterial, anti fungal and anti inflammatory effects of these secondary metabolitesin vitro and in vivo models, due to treatment of Diabetes.

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    APA: Copy

    KHAKI, A.. (2015). ANTIOXIDANT ACTIVITY, PHYTOCHEMICAL AND ETHNOPHARMACOLOGY OF MELILOTUS OFFICINALIS L. AS ANTI INFLAMMATORY TO TREAT OF DIABETIC SORE (SHORT PAPER). ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, 3(1 (9)), 73-81. SID. https://sid.ir/paper/247838/en

    Vancouver: Copy

    KHAKI A.. ANTIOXIDANT ACTIVITY, PHYTOCHEMICAL AND ETHNOPHARMACOLOGY OF MELILOTUS OFFICINALIS L. AS ANTI INFLAMMATORY TO TREAT OF DIABETIC SORE (SHORT PAPER). ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS[Internet]. 2015;3(1 (9)):73-81. Available from: https://sid.ir/paper/247838/en

    IEEE: Copy

    A. KHAKI, “ANTIOXIDANT ACTIVITY, PHYTOCHEMICAL AND ETHNOPHARMACOLOGY OF MELILOTUS OFFICINALIS L. AS ANTI INFLAMMATORY TO TREAT OF DIABETIC SORE (SHORT PAPER),” ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, vol. 3, no. 1 (9), pp. 73–81, 2015, [Online]. Available: https://sid.ir/paper/247838/en

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