PHYTOCHEMICAL, ANTIOXIDANT AND ANTIDIABETIC ACTIVITY IN AQUEOUS EXTRACT OF TRIGONELLA FOENUMGRACEUM L.

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KASSAEE SEYED MEHRDAD; GOODARZI MOHAMAD TAGHI; HAYATI RUDBARI NASIM; YAGHMAEI PARICHEHR

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Journal Paper

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Journal: Ecophytochemistry journal of Medicinal Plants Year:2016 | Volume:4 | Issue:1 (13) Page(s): 95-106

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Title

PHYTOCHEMICAL, ANTIOXIDANT AND ANTIDIABETIC ACTIVITY IN AQUEOUS EXTRACT OF TRIGONELLA FOENUMGRACEUM L.

Author(s)

KASSAEE SEYED MEHRDAD | GOODARZI MOHAMAD TAGHI | HAYATI RUDBARI NASIM | YAGHMAEI PARICHEHR | Issue Writer Certificate

Keywords

ADVANCED GLYCATION END PRODUCTSQ1

ANTI-DIABETICQ2

ANTIOXIDANTQ1

FLAVONOIDQ2

PHENOLQ2

TRIGONELLA FOENUMGRACEUM L.Q2

Abstract

Trigonella foenumgraceum L. with variety of polyphenoles which has been used as an ANTIOXIDANT and nutritive vegetable to treat of diabetes. The aim of the present study was to investigate the phytochemical, ANTIOXIDANT and antidiabetic activities of plant leave extract. The leaves were collected from medicinal garden of Hamedan during August 2014. The aqueous extract was obtained by maceration. Total PHENOL and FLAVONOID content were determined by using spectrophotometric methods. The ANTIOXIDANT activity were measured by using FRAP, ferric chelating activity, thiol and DPPH radical scavenging assay. The anti-diuretic properties, inhibition of fructose amine and ADVANCED GLYCATION END PRODUCTS formation and also albumin fragmentation by spectrophotometric, spectrofluorometric and electrophoresis methods, respectively. The results were showed that the total PHENOL content (23.87mg GAE/g), total FLAVONOID (17.29 mgQUE/g), thiolgrou (p0.26 mmoleCYE/mg) and total ANTIOXIDANT capacity (0.33mmole FeSO4E/mg). Ferric chelating ability and radical scavenging activities were both in a concentration-related manner. The aqueous extract of plant in high concentration could inhibit fructosam ineformation (70.9%) and also albumin fragmentation. Thus this extract can be used for prevention of plant -related complications of diabetes.

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APA: Copy

KASSAEE, SEYED MEHRDAD, GOODARZI, MOHAMAD TAGHI, HAYATI RUDBARI, NASIM, & YAGHMAEI, PARICHEHR. (2016). PHYTOCHEMICAL, ANTIOXIDANT AND ANTIDIABETIC ACTIVITY IN AQUEOUS EXTRACT OF TRIGONELLA FOENUMGRACEUM L.. ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, 4(1 (13)), 95-106. SID. https://sid.ir/paper/247852/en

Vancouver: Copy

KASSAEE SEYED MEHRDAD, GOODARZI MOHAMAD TAGHI, HAYATI RUDBARI NASIM, YAGHMAEI PARICHEHR. PHYTOCHEMICAL, ANTIOXIDANT AND ANTIDIABETIC ACTIVITY IN AQUEOUS EXTRACT OF TRIGONELLA FOENUMGRACEUM L.. ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS[Internet]. 2016;4(1 (13)):95-106. Available from: https://sid.ir/paper/247852/en

IEEE: Copy

SEYED MEHRDAD KASSAEE, MOHAMAD TAGHI GOODARZI, NASIM HAYATI RUDBARI, and PARICHEHR YAGHMAEI, “PHYTOCHEMICAL, ANTIOXIDANT AND ANTIDIABETIC ACTIVITY IN AQUEOUS EXTRACT OF TRIGONELLA FOENUMGRACEUM L.,” ECO-PHYTOCHEMICAL JOURNAL OF MEDICAL PLANTS, vol. 4, no. 1 (13), pp. 95–106, 2016, [Online]. Available: https://sid.ir/paper/247852/en

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